颌骨骨肉瘤3例及文献复习

目的探讨颌骨骨肉瘤的临床病理特征、诊断及鉴别诊断方法，并进行相关文献复习。 方法回顾性分析韶关市第一人民医院3例颌骨骨肉瘤临床资料，结合影像学特点，分析该病光学显微镜下的形态特征和免疫组化结果，并进行相关文献复习。 结果3例颌骨骨肉瘤，病例1发生于左上颌、病例2发生于左下颌，病例1、病例2病理诊断为颌骨普通型骨肉瘤；病例3发生于右下颌，诊断为颌骨低级别中心性骨肉瘤。颌骨骨肉瘤在临床上十分少见，与长骨骨肉瘤相比有其自身特点。 结论颌骨骨肉瘤在发病年龄，镜下特征均有所不同，临床上要注意与良性骨病相鉴别，需结合临床特征、影像学及病理镜下形态综合考虑。

Osteosarcoma of the jaws: study and literature review with 3 cases

ObjectiveTo investigate the clinicopathological features of the osteosarcoma in the jaws bones and its diagnosis, differential diagnosis and literature review. MethodsA retrospective study was made on 3 cases of osteosarcoma of the jaws in our hospital, combined with the imaging materials, to study the microscopical histology and review the literature. ResultsIn case 1 the tumor located in the left maxilla and in case 2 the tumor located in the left mandible. Both two cases were diagnosed as conventional osteosarcoma. In case 3 the lesion located in the right mandible and it was diagnosed as low-grade central osteosarcoma. The osteosarcoma of the jaws bones is rare in clinic, and it has its own characteristic compared with osteosarcoma of long bone. ConclusionsThe osteosarcoma of the jaws have its characteristic in age of onset andmicroscopical histology. It is necessary to be differentiated from benign bone diseases with data of clinical features, radiology and pathological microscopic morphology.