| 卷柏化学成分研究卷柏化学成分研究 |
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| 引用本文： | 郑晓珂,毕跃峰,冯卫生,史社坡,王继峰,牛建昭. 卷柏化学成分研究卷柏化学成分研究[J]. 药学学报, 2004, 39(4): 266-268 |
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| 作者姓名： | 郑晓珂 毕跃峰 冯卫生 史社坡 王继峰 牛建昭 |
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| 作者单位： | 1. 北京中医药大学,北京,100029
2. 河南中医学院,河南,郑州,450008 |
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| 基金项目： | 国家自然科学基金资助项目(30 371775)，河南省自然科学基金资助课题 ( 2 0 0 0 36 0 0 0 3) |
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| 摘 要： | 目的研究中药卷柏(Selaginella tamariscina (Beauv.) Spring)水提物中的化学成分。方法利用Sephadex LH-20及硅胶等色谱技术进行分离纯化,根据理化性质、光谱数据进行结构鉴定。结果得到4个化合物,分别鉴定为1-羟基-2-［2-羟基-3-甲氧基-5-(1-羟基乙基)-苯基］-3-(4-羟基-3,5-二甲氧基苯基)-丙烷-1-O-β-D-葡糖苷(卷柏苷B,I),腺苷(II),鸟苷(III),熊果苷(IV)。结论卷柏苷B为新化合物,腺苷、熊果苷、鸟苷为首次从卷柏属植物中分离得到。
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| 关 键 词： | 卷柏 卷柏苷B 腺苷 鸟苷 熊果苷 |
| 收稿时间： | 2003-05-26 |
Study on the chemical constituents of Selaginella tamariscina (Beauv.) Spring |
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| ZHENG Xiao-ke BI Yue-feng FENG Wei-sheng,SHI She-po WANG Ji-feng NIU Jian-zhao. Study on the chemical constituents of Selaginella tamariscina (Beauv.) Spring[J]. Acta pharmaceutica Sinica, 2004, 39(4): 266-268 |
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| Authors: | ZHENG Xiao-ke BI Yue-feng FENG Wei-sheng SHI She-po WANG Ji-feng NIU Jian-zhao |
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| Affiliation: | Henan College of Traditional Chinese Medicine, Zhengzhou 450008, China. |
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| Abstract: | AIM: To study the chemical constituents of Selaginella tamariscina (Beauv.) Spring. METHODS: Various chromatographic techniques were used to separate and purify the chemical constituents. Their physico-chemical properties and spectral data were used to elucidate the structures. RESULTS: Four compounds were isolated from the n-BuOH fraction of the water-extracts. Their structures were identified as 1-hydroxy-2-[2-hydroxy-3-methoxy-5-(1-hydroxyethyl)-phenyl]-3-(4-hydroxy-3,5-dimethoxy)-propane-1-O-beta-D-glucopyranoside (tamariscinoside B, I), adenosine (II), guanosine (III), arbutin (IV). CONCLUSION: Tamariscinoside B (I) is a new compound, while the others were isolated from Selaginella for the first time. |
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| Keywords: | Selaginella tamariscina (Beauv.) Spring tamariscinoside B adenosine guano sine arbutin |
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