| 草乌甲素的镇痛机制及其治疗疼痛的研究进展 |
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| 引用本文： | 徐海,姚旌.草乌甲素的镇痛机制及其治疗疼痛的研究进展[J].现代药物与临床,2023,38(10):2639-2644. |
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| 作者姓名： | 徐海 姚旌 |
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| 作者单位： | 贵州医科大学 麻醉学院, 贵州 贵阳 550004;贵州医科大学附属医院 疼痛科, 贵州 贵阳 550004 |
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| 基金项目： | 贵州省科技计划项目(黔科合基础-ZK[2023]一般389) |
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| 摘 要： | 草乌甲素具有良好的镇痛作用，用于多种疼痛的治疗。草乌甲素可作用于疼痛感知通路中的多个位点，发挥外周、中枢及其他镇痛机制。草乌甲素的临床治疗涉及到骨关节疼痛、癌性疼痛、带状疱疹相关性疼痛、急性疼痛和其他疼痛。对草乌甲素的镇痛机制和治疗各类疼痛的临床应用进行综述，以期对草乌甲素的临床治疗提供参考。
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| 关 键 词： | 草乌甲素 外周镇痛 中枢镇痛 骨关节疼痛 癌性疼痛 带状疱疹相关性疹痛 急性疼痛 |
| 收稿时间： | 2023/7/20 0:00:00 |
Research progress on analgesic mechanism of bulleyaconitine A and its treatment of pain |
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| XU Hai,YAO Jing.Research progress on analgesic mechanism of bulleyaconitine A and its treatment of pain[J].Drugs & Clinic,2023,38(10):2639-2644. |
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| Authors: | XU Hai YAO Jing |
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| Institution: | College of Anesthesiology, Guizhou Medical University, Guiyang 550004, China; Department of Pain, The Affiliated Hospital of Guizhou Medical University, Guiyang 550004, China |
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| Abstract: | Bulleyaconitine A has good analgesic effects and is used for treatment of various types of pain. Bulleyaconitine A can act on multiple targets in the pain perception pathway, playing a role in peripheral, central, and other analgesic mechanisms. The clinical treatment of bulleyaconitine A involves joint pain, cancer pain, herpes zoster associated rash pain, acute pain, etc. This article reviews the analgesic mechanism and clinical application of bulleyaconitine A in treatment of various types of pain, in order to provide reference for the clinical treatment of bulleyaconitine A. |
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| Keywords: | bulleyaconitine A peripheral analgesia central analgesia joint pain cancer pain herpes zoster associated rash pain acute pain |
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