| 苯佐卡因凝胶剂药效学实验研究 |
| |
| 引用本文： | 周卫,吴晓兰. 苯佐卡因凝胶剂药效学实验研究[J]. 药学与临床研究, 2000, 0(4) |
| |
| 作者姓名： | 周卫 吴晓兰 |
| |
| 作者单位： | 江苏省药物研究所，江苏省药物研究所 南京 210009，南京 210009 |
| |
| 摘 要： | 将苯佐卡因制成以卡波姆为基质的外用凝胶剂,进行了药效学实验、口腔粘膜刺激性实验和急性毒性实验。结果表明苯佐卡因凝胶药效明显,与对照组有显著差异;使用后口腔粘膜未见刺激性;口服及腹腔注射LD_(50)分别为1327.9 mg/kg及1222.6 mg/kg。
|
| 关 键 词： | 苯佐卡因 凝胶剂 制备 药效学试验 急性毒性试验 |
Study on Preparation of Benzocain Gel and Its Pharmacodynamics |
| |
| Zhou Wei,Wu XiaolanJiangsu Institute of Material Medica. Study on Preparation of Benzocain Gel and Its Pharmacodynamics[J]. Pharmacertical and Clinical Research, 2000, 0(4) |
| |
| Authors: | Zhou Wei Wu XiaolanJiangsu Institute of Material Medica |
| |
| Affiliation: | Nanjing 210009 |
| |
| Abstract: | This paper introduces the preparation of a topic gel- Benzocain gel made using carbomer 934P. The results of pharmacodynamics show that its effects are obvious and the LD50 are 1327. 9 mg/kg(po) and 1222. 6 mg/kg(ip). |
| |
| Keywords: | Benzocain Gel Preparation Pharmacodynamics LD50 |
| 本文献已被 CNKI 等数据库收录！ |
