脑电生物反馈对共患ADHD和LD患儿脑功能改善作用

目的探讨脑电生物反馈对共患注意缺陷多动障碍（ADHD）和学习障碍（LD）患儿脑功能的改善作用。方法应用脑电生物反馈治疗仪对48例共患ADHD和LD患儿进行治疗。采用脑电反馈仪检测脑电波功率比值，采用持续注意测验检测注意力，采用瑞文推理测验评价智力，采用酶联夹心免疫吸附测定法检测血清浓度。结果治疗后患儿θ／B、θ／SMR值较前明显下降（P〈0．01），漏报数、错误数、反应时间较前降低（P〈0．01），智商较前改善（P〈0．01），血清β—EP浓度（180．29±32.38）pg／ml，（191．01±22．85）pg／ml]较前升高（P〈0．01）。结论脑电反馈治疗能够显著改善共患ADHD和LD患儿的脑电异常、智力、注意力，且对脑电异常改善作用无左右脑半球特异性。

Effect of EEG biofeedback on improving brain function of children with comorbidity of ADHD and LD

Objective To investigate the effect of EEG biofeedback treatment on improving brain func-tion of children with Comorbidity of attention deficit hyperactivity disorder(ADHD) and Learning disorder(LD).Methods Forty-eight children with Comorbidity of ADHD and LD diagnosed according to ICD-10 received 40 sessions of EEG biofeedback treatment. Feedback was contingent on enhancing beta activity and suppressing the-ta activity. All subjects were measured at pretreatment and at posttreatment on EEG activity, Raven's Standard Progressive Matrices, Continuous Performance Task (CPT). Serum levels were measured by enzyme linked immu-nosorbent assay. Results After treatment significante decreases were observed in the EEG ratio of the theta/be-ta and theta/SMR (P<0.01), in the errors commission and errors of omiss and reaction time of CPT (P<0.01). The mean concentration of Serum β-EP(180.29±32.38) pg/ml and (191.01±22.85) pg/ml] in-creased significantly(P<0.01). IQ improve after treatment (P<0.01). Conclusion EEG biofeedback is highly effective in improving EEG spectrum,intelligence, attention of children with Comorbidity of ADHD and LD. The effect of EEG biofeedback is not hemispheric specific.