肺癌患者结核菌感染状况

目的　探讨肺结核与肺癌的相关性。方法　运用经典抗酸染色 (ZN法 )、改良抗酸染色(IK法 )、免疫组织化学染色 (ABC法 )及TB PCR方法对 3 3 0例肺癌患者结核菌感染状况进行了前瞻性研究。结果　全组 3 3 0例纤维支气管镜刷检结核菌阳性率为 2 7.88% ;93例肺癌组织标本IK法结核菌阳性率 3 8.71% ,ABC法阳性率 5 1.6 1% ;14例手术切除标本结核菌培养阳性率 5 7.14 % ;2 0例肺癌组织切片TB PCR阳性率 6 0 %。结论　肺癌患者结核菌特别是它的L型有较高的感染率。提示肺结核与肺癌之间可能有一定的相关性。

Infection of mycobacterium tuberculosis in lung cancer

Objective To investigate the relationship between pulmonary tuberculosis and lung cancer.Methods A prospective study on the infection of mycobacterium tuberculosis was carried out in 330 lung cancer patients by classic acid fast staining (ZN) and improved acid fast staining (IK) method and immunohistochemistry staining (ABC) and TB PCR methods.Results Positive rate of mycobacterium tuberculosis by ZN was 27.88% in the specimens from fiber bronchoscopic brash of 330 patients with lung cancer; the rate by IK and ABC was 38.71% and 51.61% respectively in 93 cancer tissue specimens, and 57.14% for mycobacterium tuberculosis cultivation in 14 dissected cancer tissue specimens and 60% for TB PCR in 20 tumor samples. Conclusion There is high infection rate of mycobacterium tuberculosis in lung cancer patients, especially its L form. These results suggest that there might be a relationship between pulmonary tuberculosis and lung cancer.