| 检测胞浆抗原用于急性白血病免疫分型 |
| |
| 引用本文： | 齐晖,李富荣,王新根,陈晓琳,戴勇. 检测胞浆抗原用于急性白血病免疫分型[J]. 中国医学工程, 2002, 10(6): 85-86 |
| |
| 作者姓名： | 齐晖 李富荣 王新根 陈晓琳 戴勇 |
| |
| 作者单位： | 深圳市人民医院临床医学研究中心,深圳,518020 |
| |
| 摘 要： | 目的:探讨胞浆抗原在急性白血病免疫分型中的临床意义。方法:用流式细胞仪检测42例初治急性白血病患者胞浆抗原CyCD_3,CyCD_(22),CyCD_(79a)和MPO。结果:T—ALL阳性胞浆抗原主要表达在CyCD_3,阳性率占88.9％。B—ALL阳性胞浆抗原主要表达在CyCD_(79a),AML主要表达CyMPO。结论:CyCD_3和CyCD_(79a),及MPO可分别作为T—ALL,B—ALL和AML系列特异性标志,对正确诊断白血病提供非常有价值的依据。
|
| 关 键 词： | 胞浆抗原 急性白血病 流式细胞仪 |
| 修稿时间： | 2002-07-31 |
IMMUNOPHENOTYPING OF ACUTE LEUKEMIA BY MEASURING CELL PLASMA ANTIGENS |
| |
| Qi Hui,Li Furong,Wang Xingeng,et al.. IMMUNOPHENOTYPING OF ACUTE LEUKEMIA BY MEASURING CELL PLASMA ANTIGENS[J]. China Medical Engineering, 2002, 10(6): 85-86 |
| |
| Authors: | Qi Hui Li Furong Wang Xingeng et al. |
| |
| Affiliation: | Qi Hui,Li Furong,Wang Xingeng,et al.The Clinical Medicine Research Centre,Shenzhen People's Hosptial,Shenzhen 510820 |
| |
| Abstract: | Objective:To evaluate the role of the cell plasma antigens in acute leukemia immunophenotyping. Methods: The cell plasma antigens that included CyCD3, CyCD22, CyCD79a and MPO were detected in 42 patients with acute leukemia by flow cytometer. Results:The CyCD3 expression was observed mainly in T- ALL cell plasma antigen with 88.9% postive rate. The CyCD79a and CyMPO expressed mainly in B - ALL and AML, respectively. Conclusion :CyCD3,CyCD79a and MPO can act as sequences of specific mark for T - ALL,B- ALL and AML respectively, which will benefit the diagnosis of acute leukemia. |
| |
| Keywords: | Cell Plasma Antigen Acute Leukemia Flow Cytometer |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
| 点击此处可从《中国医学工程》浏览原始摘要信息 |
|
点击此处可从《中国医学工程》下载全文 |
|
