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小百部的甾体皂甙成分
引用本文:丁怡,杨崇仁. 小百部的甾体皂甙成分[J]. 药学学报, 1990, 25(7): 509-514
作者姓名:丁怡  杨崇仁
作者单位:中国医学科学院药物研究所,中国科学院昆明植物研究所植物化学开放实验室 北京 100050,昆明 650204
摘    要:从云南产小百部(Asparagus filicinus Buch.-Ham)的根中分离到四个甾体皂甙,经光谱分析和化学降解,确定了结构,其中三个为新化合物,分别命名为小百部甙A(Ⅰ),小百部甙B(Ⅱ)和小百部甙C(Ⅲ)。另一个为已知皂甙Asp-Ⅳ的22-甲氧基化物(Ⅳ)。此外还分离到β-蜕皮甾酮(β-ecdysone,Ⅴ)。

关 键 词:小百部  甾体皂甙  菝葜皂甙元  小百部甙A  小百部甙B  小百部甙C
收稿时间:1989-04-05

STEROIDAL SAPONINS FROM ASPARAGUS FILICINUS
Y Ding and CR Yang. STEROIDAL SAPONINS FROM ASPARAGUS FILICINUS[J]. Acta pharmaceutica Sinica, 1990, 25(7): 509-514
Authors:Y Ding and CR Yang
Affiliation:Laboratory of Phytochemistry, Kunming Institute of Botany, Academia Sinica.
Abstract:Three new steroidal saponins, aspafilioside A, B and C together with a known saponin 22-methoxy ASP-IV and beta-ecdysone were isolated from the root of Asparagus filicinus Buch.-Ham. (Chinese name as xiao-bai-bu), a folk medicine of the minorities in Yunnan Province, China, used for the treatment of bronchitis, pneumonitis and cough. Their structures were established as sarsasa pogenin-3-O-beta-D-xy lopyranosyl (1----4)-beta-D-glucopyranoside (I), sarsasapogenin-3-O-beta-D-xylopyranosyl (1----4) [alpha-L-arabinopyranosyl (1----6)]-beta-D-glucopyranoside (II) and (25S)-5 beta-furost-3 beta, 22, 26-triol-3-O-beta-D-xylopyranosyl (1----4) [alpha-L-arabinopyranosyl(1----6)]-beta-D-glucopyranoside-26-O-bet a-D- glucopyranoside (III) by spectral and chemical methods.
Keywords:Asparagus filicinus Bunch. -Ham.  Steroidal saponin  Sarsasapogenin  Aspafilioside A  Aspafilioside B :Aspafilioside C  
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