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猴菇菌培养物中二个新吡喃酮化合物的分离与鉴定
引用本文:钱伏刚,徐光漪,杜上,李敏华. 猴菇菌培养物中二个新吡喃酮化合物的分离与鉴定[J]. 药学学报, 1990, 25(7): 522-525
作者姓名:钱伏刚  徐光漪  杜上  李敏华
作者单位:上海医药工业研究院,上海医药工业研究院,上海医药工业研究院,上海医药工业研究院 上海 200040,上海 200040,上海 200040,上海 200040
摘    要:从猴菇菌(Hericium erinaceus Bull pers)培养物中分得4个晶体和1个液态化合物。经鉴定,其中二个是新化合物,命名为猴菇菌素Ⅲ(Ⅲ)和Ⅳ(Ⅳ),其化学结构分别定为6-甲基-2,5-二羟甲基-γ-吡喃酮(Ⅲ)和2-羟甲基-5-(1′-羟基)-乙基-γ-吡喃酮(Ⅳ)。其余三个晶体的化学结构分别为4-氯-3,5-二甲氧基苯甲酸-O-阿拉伯糖醇酯(Ⅰ),4-氯-3,5-二甲氧基苯甲酸甲酯(Ⅲ),4-氯-3,5-二甲氧基苯甲酸(Ⅴ)。

关 键 词:猴菇菌  猴菇菌素Ⅲ  猴菇菌素Ⅳ
收稿时间:1989-04-14

ISOLATION AND IDENTIFICATION OF TWO NEW PYRONE COMPOUNDS FROM THE CULTURE OF HERICTUM ERINACEUS
Hericium erinaceus,Herierin,Herierin. ISOLATION AND IDENTIFICATION OF TWO NEW PYRONE COMPOUNDS FROM THE CULTURE OF HERICTUM ERINACEUS[J]. Acta pharmaceutica Sinica, 1990, 25(7): 522-525
Authors:Hericium erinaceus  Herierin  Herierin
Affiliation:Shanghai Institute of Pharmaceutical Industry.
Abstract:Four crystalline and one liquid compounds were isolated from the solid cultured extract of Hericium erinaceus, Two of them are new, named herein III and IV. Their chemical structures were determined as 6-methyl-2,5-dihydroxymethyl-gamma-pyranone (III) and 2-hydroxymethyl-5-alpha-hydroxy-ethyl-gamma-pyranone (IV). The others are 4-chloro-3,5-dimethoxybenzoic-O-arabitol ester, 4-chloro-3,5-dimethoxybenzoic methyl ester and 4-chloro-3,5-dimethoxybenzoic acid. In addition, a mixture of palmic and stearic acid, a mixture of behenic acid and tetracosanic acid and a mixture of 5 alpha-ergostan-3-one, 5 alpha-stigmasten-22-en-3-one and 5 alpha-stigmastan-3-one were also isolated.
Keywords:FG Qian  GY Xu   SJ Du and MH Li
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