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刺果甘草化学成分的研究
引用本文:柳江华,杨松松,付玉琴,袁昌鲁,刘波.刺果甘草化学成分的研究[J].药学学报,1990,25(9):689-693.
作者姓名:柳江华  杨松松  付玉琴  袁昌鲁  刘波
作者单位:辽宁中医学院中药系,辽宁中医学院中药系,辽宁中医学院中药系,辽宁中医学院中药系,抚顺制药厂技术科 沈阳 110032,沈阳 110032,沈阳 110032,沈阳 110032
摘    要:刺果甘草(Glycyrrhiza pallidiflora Maxim)根及根茎的甲醇提取物经盐酸甲醇反应,柱层析分离,得到五个单体。经理化常数和光谱分析,确定化合物Ⅰ为β-谷甾醇,Ⅲ为macedonic acid methylester,Ⅳ为21-dehydro-macedonic acid methyl ester,命名为刺果酸甲酯(pallidifloric acid methyl ester),Ⅴ为5-羟基-4-甲氧基异黄酮,命名为刺果甘草素(pallidiflorin)。化合物Ⅱ初步确定为具有11,13(18)异环双烯的五环三萜衍生物。其中Ⅳ是首次从植物中分得,Ⅴ为新化合物。

关 键 词:刺果甘草  macedonic  acid  methyl  ester  刺果酸甲酯  刺果甘草素
收稿时间:1989-05-31

STUDIES ON CHEMICAL CONSTITUENTS FROM GLYCYRRHIZA PALIDDIFLORA MAXIM
JH Liu,SS Yang,YQ Fu,CL Yuan and B Liu.STUDIES ON CHEMICAL CONSTITUENTS FROM GLYCYRRHIZA PALIDDIFLORA MAXIM[J].Acta Pharmaceutica Sinica,1990,25(9):689-693.
Authors:JH Liu  SS Yang  YQ Fu  CL Yuan and B Liu
Institution:Liaoning College of Traditional Chinese Medicine, Shenyang.
Abstract:Five compounds were isolated from the rhizome of Glycyrrhiza pallidiflora Maxim. Four of them were elucidated by spectroscopic and chemical methods as beta-sitosterol (II), macedonic acid methyl ester (III), 21-dehydro-macedonic acid methyl ester (IV) and 5-hydroxy-4'-methoxy isoflavone (V). VI was isolated for the first time as a natural compound, named pallidifloric acid methyl ester. V is a new compound, named pallidiflorin. Studies of the chemical structure of II are in progress.
Keywords:Glycyrrhiza pallidiflora Maxim  Macedonic acid methylester  Pallidifloric acid methyl ester  Pallidiflorin
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