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寒冷干燥环境下羊肢体枪伤骨折后血清酶含量变化
引用本文:陈建常,邢叔星,刘聪,张春浩,陈文红,张保东. 寒冷干燥环境下羊肢体枪伤骨折后血清酶含量变化[J]. 创伤外科杂志, 2010, 12(2): 163-164
作者姓名:陈建常  邢叔星  刘聪  张春浩  陈文红  张保东
作者单位:兰州军区乌鲁木齐总医院骨二科,新疆,乌鲁木齐,830000;兰州军区乌鲁木齐总医院骨二科,新疆,乌鲁木齐,830000;兰州军区乌鲁木齐总医院骨二科,新疆,乌鲁木齐,830000;兰州军区乌鲁木齐总医院骨二科,新疆,乌鲁木齐,830000;兰州军区乌鲁木齐总医院骨二科,新疆,乌鲁木齐,830000;兰州军区乌鲁木齐总医院骨二科,新疆,乌鲁木齐,830000
基金项目:全军医学科研"十一五"计划课题 
摘    要:目的观察寒冷干燥环境下羊肢体枪伤骨折后血清碱性磷酸酶(ALP),乳酸脱氢酶(LDH)和肌酸激酶(CK)的变化。方法新疆绵羊10只,置于-25℃寒冷干燥的室外3小时,77式手枪枪击一侧后肢小腿,致胫骨中段骨折。分别取受伤前、受伤后2、4、6、8、12、24小时静脉血,检测血中ALP、LDH、CK含量。结果伤后ALP无变化,LDH、CK逐渐升高,伤后8小时达峰值,此后逐渐回落。结论寒冷干燥环境可以减轻枪伤局部组织损伤,保护细胞膜,减少细胞内酶的释放。

关 键 词:枪伤  骨折  碱性磷酸酶  乳酸脱氢酶  肌酸激酶

Changes of serum enzymes in sheep with gunshot fracture on limbs in cold and dry environment
Affiliation:CHEN Jian-chang,XING Shu-xing,LIU Chong,et al. ( Second Department of Orthopedics, Urumqi General Hospital of Lanzhou Military Command, Urumqi 830000, China)
Abstract:Objective To investigate the changes of serum enzymes ( ALP, LDH, CK) in sheep suffered from gunshot fracture on limbs in cold and dry environment. Methods Ten sheep were kept in cold and dry environ- merit( -25℃ )for 3 hours,and then their single hind limbs were fractured in middle tibia with 7.7 type handgun. The contents of ALP, LDH, CK in vein blood were determined at 0,2,4,6,8,12 and 24 hours after injury. Results The content of LDH, CK tended to rise after injury, which peaked at 8 hours after injury and then dropped gradual- ly. The ALP had no changes at all. Conclusion The result shows that the partial tissue damage could be allevia- ted after gunshot injury in the cold and dry environment ,which can protect cell membrane and decrease the release of the enzymes in cells.
Keywords:gunshot injury  fracture  alkaline phosphatase  lactate dehydrogenase  creatine kinase
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