小儿支原体肺炎42例临床分析

目的：探讨小儿支原体肺炎的临床特点、治疗方法及疗效。方法：回顾性分析笔者所在医院2011年12月-2012年10月收治的42例支原体肺炎患儿的临床资料，该组患儿均经过病原菌、血清MP-IgM检测、影像学检查确诊，总结该组患儿的临床特点。其中21例患儿在常规治疗的基础上采用纸片扩散法检测肺炎支原体对常用抗生素的耐药性，选用敏感抗生素治疗，为治疗组。采用常规治疗的为对照组。比较两组患儿的临床疗效。结果：该组患者常见的临床表现为咳嗽和发热，c反应蛋白显著增高，提示肺炎支原体感染同时可合并病毒或细菌感染。治疗组的总有效率显著高于对照组（P〈O．05）。治疗组的咳嗽消失、持续发热、气喘消失的时间及住院时间均显著短于对照组（P〈O．05）。对于两组中难治性肺炎的患儿采用支气管肺泡灌洗能取得较好的效果。结论：支原体肺炎患儿常合并有细菌感染，婴幼儿以肺部表现为主，儿童期肺部体征不明显，应根据药敏试验选用敏感抗生素，提高疗效。

The Clinical Analysis of 42 Cases with Mycoplasma Pneumoniae Pneumonia in Children

Objective： To explore the clinical characteristics, therapeutic methods and curative effect of mycoplasma pneumoniae pneumonia in children.Method： To review and analyse the clinical data of 42 cases with mycoplasma pneumoniae pneumonia in children from December 2011 to October 2012 in our hospital.The patients were diagnosed through pathogens, MP-IgM in serum and imageological examination.The clinical characteristics were summarized 21 cases were chosen as treatment group which treated with sensitive antibiotics by using the disc diffusion method to test the resistance of common antibiotics of myeoplasma pneumaniae on the basis of conventional treatments.The patients treated with conventional treatments were chosen as the control group.Result： The common clinical feature were cough and fever, the ClIP was significantly higher, this feature suggested there were virus or bacterial infection in myeoplasma pneumoniae.The total efficiency in treatment group was higher than which in control group （ P〈0.05 ） .The time of cough disappear, continue fever, asthma disappear and hospitalization in treatment group were shorter which in control group （ P〈0.05 ） .The bronchoscopy with bronchoalveolar lavage in the treatment of refractory mycoplasmal pneumonia in children had better effect.Conclusion： The mycoplasma pneumoniae usually combines with bacterial infection.The pulmonary lesions is the main feature in infant, while it isn＇ t the main feature in children.The treatment according to Sensitive antibiotics by the drug sensitive test can improve the efficacy.