| HPLC法同时测定氟麻滴鼻液中的盐酸麻黄碱和ZOF的含量 |
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| 引用本文： | 陈洪轩,陈松林,黄少玲. HPLC法同时测定氟麻滴鼻液中的盐酸麻黄碱和ZOF的含量[J]. 河南大学学报(医学版), 2002, 21(3): 17-18 |
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| 作者姓名： | 陈洪轩 陈松林 黄少玲 |
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| 作者单位： | 1. 河南大学药学院,河南,开封,475001
2. 中国药科大学,南京,210009 |
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| 摘 要： | 目的 :测定盐酸麻黄碱和氧氟沙星的含量。方法 :用HPLC法 ,流动相为 :乙腈 -水 -三乙胺 (2 0 0∶80 0∶1) ,检测波长为 2 0 5nm。结果 :在测量范围内有很好的线性 ,r值分别为 0 .9999和 0 .9998。平均回收率为 10 8%和 99.7% ,RSD为 0 .0 11和 0 .0 4 0。结论 :该方法准确、灵敏、快速、简便易行。
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| 关 键 词： | 滴鼻剂 盐酸麻黄碱 ZOF HPLC |
| 文章编号： | 1008-2867(2002)03-0017-02 |
| 修稿时间： | 2002-06-25 |
Quantitative determination of ephedrine hydrochloride and ZOF by HPLC method |
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| CHEN Hong-xuan ,CHEN Song-lin ,HUANG Shao-ling. Quantitative determination of ephedrine hydrochloride and ZOF by HPLC method[J]. Journal of Henan University, 2002, 21(3): 17-18 |
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| Authors: | CHEN Hong-xuan CHEN Song-lin HUANG Shao-ling |
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| Affiliation: | CHEN Hong-xuan 1,CHEN Song-lin 1,HUANG Shao-ling 2 |
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| Abstract: | Objective: To establish a determination method of ZOF and ephedrine hydrochloride in nasal drops.Methods: With HPLC, the detection wavelength was 205 nm, and the mobile phase was acetonitrile : water : triethylamine= 200∶800∶1 (pH4.0).Results: The average recoveries and RSD for ephedrine hydrochloride were 108%(RSD=0.011). The average recoveries and RSD for ZOF were 99.7%(RSD=0.04).Conclusion: This method is accurate,sensitive and fast. |
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| Keywords: | ephedrine hydrochloride ZOF HPLC |
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