Effect of domperidone therapy on nocturnal dyspeptic symptoms of functional dyspepsia patients |
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| Authors: | Sheng-Liang Chen Jie-Ru Ji Ping Xu Zhi-Jun Cao Jian-Zhong Mo Jing-Yuan Fang Shu-Dong Xiao |
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| Affiliation: | Sheng-Liang Chen, Jie-Ru Ji, Ping Xu, Zhi-Jun Cao, Jian-Zhong Mo, Jing-Yuan Fang, Shu-Dong Xiao, Department of Gastroenterology, Shanghai Institute of Digestive Diseases, Renji Hospital, Shanghai Jiaotong University School of Medicine, 145 Middle Shandong Road, Shanghai 200001, China |
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| Abstract: | AIM:To investigate the incidence of nocturnal dyspeptic symptoms in patients with functional dyspepsia(FD) and whether prokinetic drugs can alleviate them. METHODS:Eighty-five consecutive Chinese patients with FD were included in this study.One week after single-blinded placebo run-in treatment,baseline nocturnal intragastric pH,bile reflux and nocturnal dyspeptic symptoms of eligible patients,including epigastric pain or discomfort,abdominal distention and belching, were investigated with questionnaires.Pa... |
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| Keywords: | Functional dyspepsia Nocturnal dyspeptic symptoms Duodenogastric bile reflux Intragastric pH Domperidone |
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