| HIV-1/2抗体口腔快速检测仪临床效果观察 |
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| 引用本文： | 吴安陆,赵甲,朱思国.HIV-1/2抗体口腔快速检测仪临床效果观察[J].深圳中西医结合杂志,2011,21(4):227-229. |
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| 作者姓名： | 吴安陆 赵甲 朱思国 |
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| 作者单位： | 湖北省监利县人民医院,湖北监利,433300 |
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| 基金项目： | 科技部科技型中小企业技术创新基金(10C26214424835) |
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| 摘 要： | 目的:评价HIV-1/2抗体口腔快速检测仪检测艾滋病病毒Ⅰ/Ⅱ型(HIV-1/2)抗体的敏感性和特异性,及其与血液HIV-1/2抗体检测试剂的一致性。方法:使用HIV-1/2抗体口腔快速检测仪采集并检测已知HIV感染者37例及我院性病门诊就诊患者391例口腔外牙龈黏膜渗出液(OMT)标本,同时使用ELISA检测上述人群的血清标本HIV-1/2抗体。结果:37例已知感染者口腔外牙龈黏膜渗出液及血液标本检测均为阳性;391例就诊患者中血液样本呈阳性2例,口腔外牙龈黏膜渗出液呈阳性1例。结果不同的病例1例,后经WesternBlot试验确认为阴性。该HIV-1/2抗体口腔快速检测仪的敏感性为100%,特异性为100%,与ELISA检测的一致性为99.77%。结论:HIV-1/2抗体口腔快速检测仪检测HIV-1/2抗体结果与现行的血液ELISA检测相近。其特有的无创安全、简捷易用的特点适用于不愿或不宜采血人群、艾滋病自愿咨询检测(VCT)门诊和自行检测等,也适用于医疗机构,可有效降低艾滋病职业暴露的风险。
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| 关 键 词： | 艾滋病抗体 唾液检测 口腔黏膜渗出液 HIV-1/2抗体口腔快速检测仪 |
Observation of the Clinical Effect of Rapid HIV-1/2 Antibody Test Used Oral Fluid |
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| WU An-lu,ZHAO Jia,ZHU Si-guo.Observation of the Clinical Effect of Rapid HIV-1/2 Antibody Test Used Oral Fluid[J].Shenzhen Journal of Integrated Traditional Chinese and Western Medicine,2011,21(4):227-229. |
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| Authors: | WU An-lu ZHAO Jia ZHU Si-guo |
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| Institution: | WU An-lu,ZHAO Jia,ZHU Si-guo(Jianli County People's Hospital,Hubei Jianli 433300) |
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| Abstract: | Objective To assess the sensitivity and specificity of Rapid HIV-1/2 Antibody Test Used Oral Fluid for HIV-1/2 antibodies testing in human oral mucosal transudate(OMT) specimens,and compare the consistency to the test reagent for HIV-1/2 antibody testing in blood specimens.Methods Paired serum and OMT specimens were collected from 37 cases known as HIV-infected sufferers and 391 cases of doctors' office visiting in the skin&venereal division outpatients.OMT specimens were collected and tested by Rapid HIV-1... |
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| Keywords: | HIV-1/2 antibody Oral Fluid Test Human oral mucosal transudate specimens Rapid HIV-1/2 Antibody Test Used Oral Fluid |
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