| 血清胱抑素C对糖尿病肾病诊断价值的Meta分析 |
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| 引用本文： | 王慧,罗炜.血清胱抑素C对糖尿病肾病诊断价值的Meta分析[J].热带医学杂志,2010,10(3). |
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| 作者姓名： | 王慧 罗炜 |
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| 作者单位： | 广州医学院第一附属医院,广州,510120 |
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| 摘 要： | 目的 评价血清胱抑素C在诊断糖尿病肾病中的价值.方法 检索多个数据库,对相关文献进行系统评价,用随机效应模型计算纳入研究的总灵敏度、特异度及其它指标,绘制受试者工作特征曲线以探讨本试验的总体诊断特性.结果 按照选择标准最终有9项独立研究纳入本次meta分析,合并灵敏度与特异度分别为85%和86%,合并阳性拟然比与阴性拟然比分别为6.23和0.17,合并诊断优势比为54.59,SROC曲线下面积0.9435,SE为0.0273.结论 血清胱抑素C水平的检测有助于评估肾小球滤过功能,对糖尿病肾病患者早期肾损害有一定的诊断价值.
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| 关 键 词： | 胱抑素C 糖尿病.肾病 系统评价 |
Meta-Analysis of Diagnostic Values of Serum Cystatin C in Diabetic Nephropathy Patients |
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| WANG Hui,LUO Wei.Meta-Analysis of Diagnostic Values of Serum Cystatin C in Diabetic Nephropathy Patients[J].Journal Of Tropical Medicine,2010,10(3). |
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| Authors: | WANG Hui LUO Wei |
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| Institution: | WANG Hui,LUO Wei(The First Affiliated Hospital of Guangzhou Medical College,Guangzhou 510120,China) |
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| Abstract: | Objective To evaluate the value of serum Cystatin C in the diagnosis of diabetic nephropathy.Methods Systematic review of various data bases was performed in this study.Data on the sensitivity,specificity and other measures of value of pleural concentrations of Cystatin C in the diagnosis of diabetic nephropathy were pooled and analyzed using random effects models.Summary receiver operating characteristic(SROC) curves were used to summarize the overall test performance.Results Data from nine independent stu... |
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| Keywords: | Cystatin C diabetic nephropathy systematic review |
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