人工授精联合卵泡穿刺术治疗未破裂卵泡黄素化不孕中的应用

目的:探讨人工授精联合卵泡穿刺术治疗未破裂卵泡黄素化(LUFS)不孕中的应用。方法:选择2013年4月至2016年4月我院接诊的100例LUFS不孕患者,通过随机数表法分为观察组和对照组,各50例。对照组在促排卵治疗后进行正常性生活,观察组在促排卵治疗后实行卵泡穿刺术联合人工授精。比较两组治疗效果。结果:在治疗后围排卵期卵巢动脉血流中,观察组搏动指数(PI)、阻力指数(RI)低于对照组,最大收缩速度(PSV)高于对照组(P0.05);治疗后,观察组卵泡刺激素(FSH)、黄体生成素(LH)、雌二醇(E_2)均高于对照组(P0.05);观察组排卵率、妊娠率明显比对照组高(P0.05),两组患者流产率无显著差异(P0.05)。结论:LUFS不孕患者在阴道超声阴道下实施人工授精联合卵泡穿刺术效果显著,其可有效促进排卵,提高妊娠率,值得应用推广。

Artificial insemination joint follicular aspiration in treatment of luteinized unruptured follicle syndrome infertility

Objectives:To study the application of artificial insemination joint follicular aspiration in the treatment of luteinized unruptured follicle syndrome (LUFS) infertility.Methods:100 patients with LUFS from April 2013 to April 2016 in our hospital were researched and were randomly divided into observation and control groups,each of 50 cases.The control group had normal sexual life after ovulation induction,while the observation group received follicular aspiration and artificial insemination after ovulation induction.The treatment effect was compared between the two groups.Results:In the ovarian artery blood flow after treatment,the pulsatile index (PI),resistance index (RI) in the observation group were lower than those in the control group,while peak systolic velocity (PSV) was higher than the control group (P ＜ 0.05).After treatment,the follicle stimulating hormone (FSH),progesterone (LH),estradiol (E2) in the observation group was higher than the control group (P ＜0.05);the ovulation rate and pregnancy rate in observation group were significantly higher than the control group (P ＜ 0.05),without significant difference in abortion rate between the two groups (P ＞ 0.05).Conclusion:Artificial insemination combined with follicular puncture is of significant effect in treating LUFS infertility patients,which can effectively promote ovulation and improve pregnancy rate,thusly worthy of application and promotion.