中医五行音乐治疗对试管婴儿妊娠结局的影响

目的:探讨中医五行音乐治疗对体外受精-胚胎移植(IVF-ET)患者焦虑、抑郁情绪的缓解及对妊娠结局的促进。方法:使用抑郁自评量表(SDS)、焦虑自评量表(SAS)对行IVF-ET的患者进行调查,筛选出100例患者,采用简单随机化分组法将其分为两组,每组各50例。其中A组为中医五行音乐组,B组为空白组;实验自患者进入IVF用药周期日开始,A组每周进行1次治疗,B组不做处理,实验到移植后4周确定是否为临床妊娠时结束;对比两组干预前后SDS结果、中医症侯积分、妊娠结局。结果:干预后A组患者SDS结果显著低于B组(P0.01),A组干预前后SDS评分差异显著(P0.01);干预后A组患者中医症侯积分显著低于B组(P0.05),B组SDS结果、SAS评分,中医症侯积分较前无显著差异;A组优质胚胎数、临床妊娠率较B组高,但组间比较无显著差异。结论:中医五行音乐具有改善患者焦虑、抑郁情绪的功效;中医五行音乐疗法有助于改善患者不孕症状,对提高临床妊娠率具有积极作用。

Effects of traditional Chinese medicine psychotherapy on the pregnancy outcomes of patients with in vitro fertilzation and embryo transplantation: application of five-element music therapy

Objectives:To explore the outcome of traditional Chinese medicine and psychological treatment (TCM and five elements of music therapy) on the depression and pregnancy outcomes of IVF-ET patients.Methods:Self-rating depression scale was used to investigate IVF-ET patients.A total of 100 patients (SDS standard score≥50) were divided into two groups with 50 cases in each group.Group A was treated with TCM five elements music therapy.Group B was blank.The experiment began from patients getting into IVF cycle.The clinical pregnancy outcome was collected at 4 weeks after transplantation.Before pregnancy,patients of group A got treatment once a week.Group B received no operation.The results of SDS,quantization table for TCM syndrome differentiation and pregnancy outcomes were compared.Results:The results of SDS of group A was significantly lower than that of group B (P ＜ 0.01) after the intervention.The quantization for TCM syndrome differentiation of group A was significantly lower than that before intervention (P ＜ 0.05).Number of high quality embryos and pregnancy in group A was more than that in group B.But there was no difference between the two groups.Conclusion:TCM five elements music therapy can improve patients' depression.The effect is superior to light music and it has a positive role in promoting clinical pregnancy rate.