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Quantitative analysis of the tomographic technetium-99m MIBI (99mTc-MIBI) myocardial bullseye display: Application to diagnosis of coronary artery disease
Authors:Gao Zai-rong  Zhang Yong-xue  Hu Jia  Xu Wen-dai
Affiliation:(1) Department of Nuclear Medicine, Xiehe Hospital, Tongji Medical University, 430022 Wuhan
Abstract:Summary In this study, the99mTc-MIBI myocardial bullseye display of 31 healthy persons and 34 patients with myocardial ischemia and 17 patients with myocardial infarction were analyzed quantitatively, and compared with the results of myocardial tomography analysis and qualitative bullseye analysis. The sensitivities of the three methods were 88.2%, 91.2% and 94.1% respectively (P>0.05), and the specificities were 93.5%, 83, 9% and 83.9% respectively (P<0.05). On the other hand, the quantitative analysis obviously outperformed the other two methods in the detection of ischemic segments of myocardhum near infarction zone (P<0.01). The quantitative analysis of99mTc-MLBI myocardial bullseye (quantitative bullseye) was an objective, specific and sensitive method for diagnosis of coronary artery disease.
Keywords:technetium-99m MIBI  myocardial imaging  SPECT  bullseye  quantitative analysis  coronary artery disease
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