不同卵泡发育时间段卵泡抽吸术对多囊卵巢患者的影响

目的观察不同卵泡发育时间段卵泡抽吸术对多囊卵巢患者的影响。方法 2009年1月～2011年2月在笔者所在医院就诊,符合PCOS诊断标准的不孕患者62例,随机分为两组,每组31例,分别在卵泡发育期和卵泡成熟期穿刺抽吸卵泡。B超监测排卵后指导同房,观察未孕患者穿刺前及第1次穿刺后促黄体生成激素、卵泡刺激素、睾酮、窦卵泡数目;观察两组患者妊娠率,卵巢过激发生率、流产率、人绒毛膜促性腺激素用量。结果 1组患者多胎妊娠率较2组显著增高（P〈0.05）;流产率、OHSS发生率显著下降（P〈0.05）;1、2组未孕患者穿刺前较第一次穿刺后LH、T水平显著下降（P〈0.05）;FSH差异无统计学意义（P〉0.05）;1组未孕患者第1次穿刺后较穿刺前窦卵泡数目显著减少（P〈0.05）。结论卵泡穿刺术可提高降低患者LH和T水平,减少窦卵泡数目,减少OHSS的发生率,临床可根据患者对促排卵药物的敏感性、卵巢被膜的厚度等选择着合适的时间进行穿刺。

Effects of follicle puncture in different growth in patients with polycystic ovary syndrome

Objective To observe the effects of follicle puncture in different follicle growth in patients with polycystic ovary syndrome. Methods 2009 January～2011 February in the hospital,accord the PCOS criteria, were randomly divided into two groups,31 cases in each group,in the follicular development and ovarian follicle mature follicle aspiration.B ultrasound monitoring after ovulation guidance again,observation of nonpregnant patients puncture before and 1 after the puncture of luteinizing hormone（LH）,follicle stimulating hormone（FSH）,T,antral follicle number;two groups were observed in patients with pregnancy, ovarian hyperstimulation（OHSS） incidence rate,miscarriage rate,human chorionic gonadotropin. Results After first follicle puncture,all the patients have declined in LH,T significantly（P 0.05）.The antral follicle counts were declined too（P 0.05）.The rates of OHSS and abortion reduced significantly in 1 group than 2 group（P 0.05）. Conclusion Follicle puncture is an effective method for treating PCOS,we can select different follicle growth moment in accord with individual difference of patients.