| 内皮祖细胞与胶质瘤关系的研究进展 |
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| 引用本文： | 张军霞,尤永平,傅震. 内皮祖细胞与胶质瘤关系的研究进展[J]. 医学研究生学报, 2007, 20(1): 94-96 |
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| 作者姓名： | 张军霞 尤永平 傅震 |
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| 作者单位： | 南京医科大学第一附属医院神经外科,江苏南京,210029 |
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| 基金项目： | 江苏省医学科技发展基金 |
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| 摘 要： | 内皮祖细胞（EPC）作为内皮细胞的前体细胞，经动员入外周血，能特异性归巢胶质瘤并参与肿瘤血管生成，但其机制目前尚不明了。内皮祖细胞有潜力成为细胞靶向载体，有助于研究胶质瘤血管生成机制及内皮祖细胞介导的靶向血管生成治疗胶质瘤的作用机制。
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| 关 键 词： | 内皮祖细胞 胶质瘤 归巢 基因治疗 |
| 文章编号： | 1008-8199(2007)01-0094-03 |
| 修稿时间： | 2006-03-12 |
The application of endothelial progenitor cells in glioma |
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| ZHANG Jun-xia,YOU Yong-ping,FU Zhen. The application of endothelial progenitor cells in glioma[J]. Bulletin of Medical Postgraduate, 2007, 20(1): 94-96 |
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| Authors: | ZHANG Jun-xia YOU Yong-ping FU Zhen |
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| Abstract: | Endothelial progenitor cells(EPC),which have the capacity to differentiate into mature endothelial cells,have been found to home to and incorporate into the angiogenic vasculature of growing tumors with high specificity once mobilized into the circulation.Yet the mechanism still remains unclear.EPC have potential as spatial-specific delivery vehicles.Thus,further studies on the mechanisms of tumor neovascularization and tumor therapy in glioma using genetically engineered EPC as angiogenesis-selective vectors will be of help to explore the potential in the basic and clinical application of EPC in(glioma.) |
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| Keywords: | Endothelial progenitor cell Glioma Homing Gene therapy |
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