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针刺对妊娠末期大鼠的促宫缩作用
引用本文:刘喆,刘红菊,邓海平.针刺对妊娠末期大鼠的促宫缩作用[J].上海针灸杂志,2003,22(1):24-26.
作者姓名:刘喆  刘红菊  邓海平
作者单位:1. 广州中医药大学,广东,510405
2. 上海中医药大学,上海,200032
摘    要:目的:探讨针刺宫缩作用的机理。方法:将妊娠末期大鼠随机分为空白组、麻油组、针刺组、临产组,用放免法测定羊水雌二醇(E2)、孕激素(P)、羊膜前列腺素E2(PGE2)、血浆内皮素(ET)、血清一氧化氮(NO)。结果:针刺可明显提高雌激素孕激素比值,增加内皮素、一氧化氮、前列腺素E2含量,但不改变内皮互一氧化氮比值。结论:针刺促宫缩作用的途径可能与改变各宫缩物质的含量或比例有关,从而促进分娩发动。

关 键 词:子宫收缩  妊娠末期  动物实验  针刺疗法  作用机理  放免法
文章编号:1005-0957(2003)01-0024-03
修稿时间:2001年12月6日

Mechanism of Acupuncture in Promoting Uterine Contraction in Late Pregnancy Rats
LIU Zhe ,LIU Hongju ,DENG Haiping . Guangzhou College of Traditional Chinese Medicine,Guangdong,China.Mechanism of Acupuncture in Promoting Uterine Contraction in Late Pregnancy Rats[J].Shanghai Journal of Acupuncture and Moxibustion,2003,22(1):24-26.
Authors:LIU Zhe  LIU Hongju  DENG Haiping Guangzhou College of Traditional Chinese Medicine  Guangdong    China
Affiliation:LIU Zhe 1,LIU Hongju 2,DENG Haiping 2 1. Guangzhou College of Traditional Chinese Medicine,Guangdong,510405,China, 2. Shanghai University of TCM,Shanghai 200032,China
Abstract:Objective To observe the mechanism of acupuncture in promoting uterine contraction. Methods Rats with late pregnancy were randomized into control group, castor-oil group, acupuncture group and labor group. Radioimmunoassay was used to detect estrogen (E 2), progesterone (P), protaglandin E 2 (PGE 2), endothelin (ET) and nitirc oxide (NO). Results Acupuncture can increase E/P, ET, NO and PGE 2, but does not alter ET/NO. Conclusion Acupuncture may change the substances in relation to uterine contraction, and eventually promote labor.
Keywords:Acupuncture  Uterine contraction  Pregnancy trimester  third  Rats  Animals  laboratory Estrogens  Progestational hormones  Prostaglandins E  Endothelins  Nitric oxide
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