PET scans in radiotherapy planning of lung cancer |
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Authors: | De Ruysscher Dirk Nestle Ursula Jeraj Robert Macmanus Michael |
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Affiliation: | a Radiation Oncologist, Maastricht University Medical Center, Department of Radiation Oncology (MAASTRO Clinic), GROW School for Oncology and Developmental Biology, Maastricht, The Netherlands b Radition Oncologist and Nuclear Medicine Specialist, Department for Radiation Oncology, University Hospital, Freiburg, Germany c Physicist, University of Wisconsin, Departments of Medical Physics, Human Oncology, Radiology and Biomedical Engineering, Madison, WI, USA d Radiation Oncologist, Department of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia |
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Abstract: | Accurate delineation of the primary tumor and of involved lymph nodes is a key requisite for successful curative radiotherapy in non-small cell lung cancer (NSCLC). In recent years, it has become clear that the incorporation of FDG PET-CT scan information into the related processes of patient selection and radiotherapy planning has lead to significant improvements for patients with NSCLC. The use of FDG PET-CT information in radiotherapy planning allows better target volume definition, reduces inter-observer variability and encourages selective irradiation of involved mediastinal lymph nodes. PET-CT also opens the door for innovative radiotherapy delivery and the development of new concepts. However, care must be taken to avoid a variety of technical pitfalls and specific education is necessary, for clinicians and physicists alike. |
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Keywords: | PET Radiotherapy Lung cancer Planning Delineation |
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