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Minimal effects of acute liver injury/acute liver failure on hemostasis as assessed by thromboelastography
Authors:Stravitz R Todd  Lisman Ton  Luketic Velimir A  Sterling Richard K  Puri Puneet  Fuchs Michael  Ibrahim Ashraf  Lee William M  Sanyal Arun J
Institution:1 Section of Hepatology and Hume-Lee Transplant Center, Virginia Commonwealth University, Richmond, VA, USA
2 Department of Anesthesiology, Virginia Commonwealth University, Richmond, VA, USA
3 Department of Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
4 Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, TX, USA
Abstract:
Keywords:ALI  acute liver injury  ALF  acute liver failure  INR  international normalized ratio of prothrombin time  TEG  thromboelastogram/thromboelastography  PT  prothrombin time  ICP  intracranial pressure  AT  antithrombin  aPTT  activated partial thromboplastin time  R-time  reaction time of TEG  K-time  kinetic time of TEG  MA  maximum amplitude of TEG  SIRS  systemic inflammatory response syndrome  WBC  white blood cell count  LY-30  clot lysis in 30   min  CVVH  continuous veno-veno hemofiltration  BMI  body mass index  APAP  acetaminophen (paracetamol)  MAP  mean arterial pressure  OLT  orthotopic liver transplantation  TFS  transplant-free survival  MELD  model for end-stage liver disease score  ADAMTS13  a disintegrin and metalloprotease with thrombospondin type-1 motifs 13  vWF  von Willebrand factor
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