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Endogenous mouse mammary tumor virus DNA is distributed among multiple mouse chromosomes. |
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| Authors: | V L Morris C Kozak J C Cohen P R Shank P Jolicoeur F Ruddle H E Varmus |
| Affiliation: | 1. Department of Microbiology and Immunology, University of Western Ontario, London, Ontario N6A 5C1, Canada;2. Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20014, USA;3. Department of Microbiology, University of California, San Francisco, California 94144, USA;4. Institute de Recherches, Cliniques de Montreal, 110 West Pine Avenue, Montreal, Quebec H2W 1R7, Canada;5. Department of Biology, Yale University, New Haven, Connecticut 16520, USA |
| Abstract: | We have examined the distribution of endogenous mouse mammary tumor virus-specific DNA in the genome of A/HeJ mice by using molecular hybridization and restriction endonucleases to analyze DNA from mouse-hamster hybrid clones that segregate mouse chromosomes. We have found that MMTV sequences are located on at least three separate chromosomal pairs, including chromosome number four. |
| Keywords: | Author to whom requests for reprints should be addressed. |
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