我国10288例卵巢恶性肿瘤的分布及组织学类型

目的：总结我国卵巢恶性肿瘤的分布及组织学分类特点,以期对卵巢肿瘤的防治有所裨益。方法：对1980－1989年10年间我国24个省、市共57所医院卵巢恶性肿瘤的病理检查资料,按WHO分类法进行登记统计,对原诊断不明者,按统一分类标准复查病理切片后再确定其分类。结果：10年间我国24个省、市所登记的卵巢肿瘤共42197例,其中卵巢恶性肿瘤10288例,为24．4％;在卵巢恶性肿瘤中,上皮性肿瘤5650例,为54．9％;生殖细胞肿瘤1871例,占18．2％;性索间质肿瘤873例,占8．5％;卵巢转移性肿瘤1003例,占9．7％;其他卵巢肿瘤891例,占8．7％。长江以南恶性肿瘤5437例,占52．8％,而长江以北4851例,占47．2％。不同组织学类型卵巢恶性肿瘤的分布在我国6大行政区和长江南北存在差异。卵巢上皮性恶性肿瘤中,交界性和恶性之比为1．0：5．9,交界性肿瘤中浆液性和黏液性所占比例是相似的;卵巢上皮性恶性肿瘤中,浆液性所占比例最高。结论：我国卵巢恶性肿瘤中,54．9％为上皮性恶性肿瘤,其次为生殖细胞肿瘤、性索间质肿瘤等。

Histological classification in 10 288 cases of ovarian malignant tumors in China

OBJECTIVE: The histological types of ovarian tumors were investigated and analyzed in China in order to compare with those in other countries, which will benefit to the prevention and treatment of ovarian carcinoma. METHODS: The pathological data from 42 197 cases of ovarian tumors in ten years during 1980 to 1989 were registered according to the WHO classification for ovarian tumors. Some unsure cases pathologically in the previous diagnosis should be reconfirmed according to the WHO classification. RESULTS: Forty-two thousand one hundred and ninety seven cases of ovarian tumors were selected from all tumors in 21 provinces and 3 major regional cities in China. There were 10 288 (24.4%) malignant tumors in all cases. They were composed by 5 650 (54.9%) cases of epithelial tumors, 1 871 (18.2%) cases of germ cell tumors, 873 (8.5%) cases of sex cord tumors, 1 003 (9.7%) cases of secondary tumors, and 891 (8.7%) cases of other tumors. The malignant tumors constituent ratios were 52.8% and 47.2% respectively in the north and south of the Yangtze River. The histological types of ovarian tumors were about the same ratios, but the malignant tumors were different in Chinese 6 major administrative region and also in the region both north and south of the Yangtze River. The ratio of borderline epithelial ovarian tumors to epithelial carcinoma was 1.0:5.9. Borderline serous cystadenocarcinoma appeared to be similar to borderline mucinous cystadenocarcinoma in frequency. Serous cystadenocarcinoma was found to be the most frequent one in malignant epithelial tumors. CONCLUSIONS: Compared with reports abroad, the different types of malignant ovarian tumors in China represent a different distributive pattern. The malignant epithelial ovarian tumors were lower than that in other countries, while the malignant germ cell tumors and sex cord stromal tumors were 6 and 3 times higher than those abroad, the main metastasizing tumors come from gastroenteric carcinoma.