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| 阿奇霉素序贯治疗小儿支原体肺炎疗效及副作用观察 | |
| 引用本文： | 张文辉,翁小琴,吴星恒.阿奇霉素序贯治疗小儿支原体肺炎疗效及副作用观察[J].江西医药,2011,46(11):977-979. |
| 作者姓名： | 张文辉 翁小琴 吴星恒 |
| 作者单位： | 1. 深圳市光明新区公明人民医院儿科,深圳,518106 2. 深圳市光明新区公明人民医院供应室 3. 南昌大学第一附属医院儿科,南昌,330006 |
| 摘 要： | 目的评价阿奇霉素序贯治疗小儿支原体肺炎的疗效及安全性。方法将12；1例肺炎支原体肺炎的患儿随机分为阿奇霉素序贯组及对照组。阿奇霉素序贯组62例，给予红霉素30mg／（kg·d），分2次静脉滴注，治疗3—5d后予阿奇霉素口服序贯治疗，10mg／（kg．d），每周连服3d停用4d为1疗程，共3疗程；对照组59例，静滴红霉素30mg／（kg·d），分2次静脉滴注，共14d。治疗2周后进行疗效评定及副作用统计。结果阿奇霉素序贯组总有效率90．3％，对照组总有效率71．1％，两者有显著性差异（X^2=10．51，P〈0．05）；阿奇霉素序贯组总不良反应发生率27.4％，对照组总不良反应发生率67．8％，两者有显著性差异（X^2=13．63，／9〈0．05）。结论阿奇霉素序贯治疗小儿支原体肺炎有效安全。 |
| 关 键 词： | 阿奇霉素 红霉素 序贯治疗 支原体肺炎 安全性 |
Effects and safety of Azithromycin sequential therapy in the treatment of mycoplasma pneumonia in children |
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| Zhang Wenhui,Weng Xiaoqin,Wu Xingheng.Effects and safety of Azithromycin sequential therapy in the treatment of mycoplasma pneumonia in children[J].Jiangxi Medical Journal,2011,46(11):977-979. | |
| Authors: | Zhang Wenhui Weng Xiaoqin Wu Xingheng |
| Institution: | Zhang Wenhui,Weng Xiaoqin,Wu Xingheng.Department of pediatrics,Guangming new area Gongming people's hospital,Shenzhen 518106,China |
| Abstract: | Objective To evaluate the effects and safety of Azithromycin sequential therapy in the treatment of mycoplasma pneumonia in children.Methods 121 patients with mycoplasma pneumonia were randomly divided into 2 groups:the Azithromycin sequential group and the control group.(1)The Azithromycin sequential group(62 cases) were given erythromycin 15mg/kg,ivgtt,q12h for 3-5d at the first stage.At the sequential stage,Azithromycin was administered 10mg/kg,qd,orally from day 1 to day 3 and then stoped for 4 days in ... |
| Keywords: | Azithromycin erythromycin sequential therapy mycoplasma pneumonia safety |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |