| 血清丙氨酸氨基转移酶轻度异常的慢性乙型肝炎肝脏病理分析 |
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| 引用本文： | 袁桂才,陈爱珍,王伟新,朱幼芙. 血清丙氨酸氨基转移酶轻度异常的慢性乙型肝炎肝脏病理分析[J]. 南昌大学学报(医学版), 2011, 0(10) |
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| 作者姓名： | 袁桂才 陈爱珍 王伟新 朱幼芙 |
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| 作者单位： | 宜春学院附属医院感染科;广州南方医院感染科; |
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| 摘 要： | 目的分析丙氨酸氨基转移酶轻度异常的慢性乙型肝炎的肝脏病理特征,探讨慢性乙型肝炎患者性别、年龄与肝脏病理的关系。方法对209例丙氨酸氨基转移酶轻度异常的慢性乙型肝炎患者采用全自动生化检测仪检测血清丙氨酸氨基转移酶、AST的水平,乙型肝炎病毒的血清标志物(HBsAg、HBeAg)采用荧光定量法检测,行肝穿刺活检及肝组织病理检查。结果 209例患者血清丙氨酸氨基转移酶45～80U.L-1,血清AST 45～80U.L-1。HBeAg阳性120例,HBeAg阴性89例。209例患者肝脏均有病理改变,异常率为100.0%(209/209)。G1为24.4%(51/209),G2为36.8%(77/209),G3为33.0%(69/209),G4为5.7%(12/209),G2-G4为75.6%(158/209);S1为42.1%(88/209),S2为37.3%(78/209),S3为13.9%(29/209),S4为6.7%(14/209),S2-S4为57.9%(121/209)。男性患者肝组织炎症及肝组织纤维化发生率与女性比较差异均无统计学意义(均P>0.05)。<20岁、≥20～<29岁、≥29～<40岁患者肝...
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| 关 键 词： | 肝炎 乙型 慢性 丙氨酸氨基转移酶 AST 病理 血清 |
Pathological Analysis of Chronic Hepatitis B with Mild Abnormalities of Alanine Aminotransferase |
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| YUAN Gui-cai,CHEN Ai-zhen,WANG Wei-xin,ZHU You-fu. Pathological Analysis of Chronic Hepatitis B with Mild Abnormalities of Alanine Aminotransferase[J]. Journal of Nanchang University(Medical Science), 2011, 0(10) |
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| Authors: | YUAN Gui-cai CHEN Ai-zhen WANG Wei-xin ZHU You-fu |
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| Affiliation: | YUAN Gui-cai1,CHEN Ai-zhen1,WANG Wei-xin1,ZHU You-fu2(1.Department of Infectious Diseases,the Affiliated Hospital of Yichun College,Yichun 336000,China,2.Department of Infectious Diseases,the Nanfang Hospital of Guangzhou,Guangzhou 510510,China) |
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| Abstract: | Objective To analyze the liver pathology of chronic hepatitis B with mild abnormalities of alanine aminotransferase(ALT),and to explore the relationship of gender and age to liver pathology in patients with chronic hepatitis B.Methods Needle biopsy of the liver and histopathological examination were performed in 209 chronic hepatitis B patients with mild abnormalities of ALT.The levels of serum ALT and aspartate aminotransferase(AST) were measured using automatic biochemical analyzer.Serum markers of hepati... |
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| Keywords: | hepatitis B chronic alanine aminotransferase aspartate aminotransferase |
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