Time‐resolved three‐dimensional magnetic resonance digital subtraction angiography without contrast material in the brain: Initial investigation |
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| Authors: | Masaaki Hori MD Nobuyuki Shiraga MD Yasushi Watanabe RT Shigeki Aoki MD Sachiko Isono BS Masao Yui MS Kuni Ohtomo MD Tsutomu Araki MD |
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| Affiliation: | 1. Department of Radiology, University of Yamanashi, Yamanashi, Japan;2. Department of Radiology, Toho University Omori Medical Center, Tokyo, Japan;3. Department of Radiology, University of Tokyo, Tokyo, Japan;4. Department of Radiology, School of Medicine, Juntendo University, Tokyo, Japan;5. Toshiba Medical Systems, Tokyo, Japan;6. MR Imaging Department, Toshiba Medical Research and Development Center, Tochigi, Japan |
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| Abstract: | ![]()
Purpose To evaluate a novel magnetic resonance (MR) angiography (MRA) of three‐dimensional (3D) MR digital subtraction angiography (MRDSA) without contrast material, which is essentially 3D true steady‐state free precession (SSFP) with selected inversion recovery (IR) pulse using multiple cardiac phase acquisitions with a short increment delay in the assessment of normal cranial arteries, as a feasibility study before clinical use. Materials and Methods Serial MRA images using 3D MRDSA without contrast material were acquired from 10 healthy volunteers. Visualization of normal cranial arteries with time‐spatial labeling inversion pulse (Time‐SLIP) MRDSA was qualitatively compared with the conventional MRA method, 3D time‐of‐flight (TOF)‐MRA. Results In all volunteers, serial 3D MRDSAs containing hemodynamic information were successfully imaged. The results of visualization of the branches of the cranial arteries with Time‐SLIP MRDSA were comparable to those of 3D TOF‐MRA. The mean scores ± standard deviations for normal cerebral arteries (internal carotid arteries, middle cerebral arteries, anterior cerebral arteries, posterior cerebral arteries, and basilar arteries) were 2.4 ± 0.5, 2.3 ± 0.5, 2.0 ± 0.7, 2.3 ± 0.7, and 2.5 ± 0.7, respectively. Conclusion Time‐SLIP 3D MRDSA is a simple method for obtaining hemodynamic information. Although more MR sequence improvement is needed, it can play an important role in assessing cranial arteries without contrast material. J. Magn. Reson. Imaging 2009;30:214–218. © 2009 Wiley‐Liss, Inc. |
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| Keywords: | MR angiography MRDSA contrast material hemodynamic information cranial artery |
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