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Whole heart magnetization‐prepared steady‐state free precession coronary vein MRI
Authors:Christian T Stoeck MSc  Yuchi Han MD  Dana C Peters PhD  Peng Hu PhD  Susan B Yeon MD  Kraig V Kissinger BS  RT  Beth Goddu RT  Lois Goepfert RN  MS  Warren J Manning MD  Sebastian Kozerke PhD  Reza Nezafat PhD
Institution:1. Department of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts;2. Institute for Biomedical Engineering, University and ETH Zurich, Switzerland;3. Department of Radiology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts
Abstract:

Purpose

To compare two coronary vein imaging techniques using whole‐heart balanced steady‐state free precession (SSFP) and a targeted double‐oblique spoiled gradient‐echo (GRE) sequences in combination with magnetization transfer (MT) preparation sequence for tissue contrast improvement.

Materials and Methods

Nine healthy subjects were imaged with the proposed technique. The results are compared with optimized targeted MT prepared GRE acquisitions. Both quantitative and qualitative analyses were performed to evaluate each imaging method.

Results

Whole‐heart images were successfully acquired with no visible image artifact in the vicinity of the coronary veins. The anatomical features and visual grading of both techniques were comparable. However, the targeted small slab acquisition of the left ventricular lateral wall was superior to whole‐heart acquisition for visualization of relevant information for cardiac resynchronization therapy (CRT) lead implantation.

Conclusion

We demonstrated the feasibility of whole‐heart coronary vein MRI using a 3D MT‐SSFP imaging sequence. A targeted acquisition along the lateral left ventricular wall is preferred for visualization of branches commonly used in CRT lead implantation. J. Magn. Reson. Imaging 2009;29:1293–1299. © 2009 Wiley‐Liss, Inc.
Keywords:3D SSFP whole‐heart MRI  coronary vein imaging  magnetization transfer contrast
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