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Prevalence of Germline Mutations Associated With Cancer Risk in Patients With Intraductal Papillary Mucinous Neoplasms
Authors:Michael Skaro  Neha Nanda  Christian Gauthier  Matthäus Felsenstein  Zhengdong Jiang  Miaozhen Qiu  Koji Shindo  Jun Yu  Danielle Hutchings  Ammar A. Javed  Ross Beckman  Jin He  Christopher L. Wolfgang  Elizabeth Thompson  Ralph H. Hruban  Alison P. Klein  Michael Goggins  Laura D. Wood  Nicholas J. Roberts
Affiliation:1. Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland;2. The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland;3. Department of Medical Oncology, Sun Yat-Sen University Cancer Center; State Key Laboratory of Oncology in South China, Guangzhou, China;4. Collaborative Innovation Center for Cancer Medicine, Guangzhou, China;5. Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland;6. Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, Maryland;7. Department of Epidemiology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland;8. Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland
Abstract:
Keywords:Pancreas  Cancer  Genetics  Predisposition  bp  base pair  ExAC  Exome Aggregation Consortium  IPMN  intraductal papillary mucinous neoplasm  MAF  minor allele frequency  PDAC  pancreatic adenocarcinoma  PARP-1  poly [ADP-ribose] polymerase-1
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