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婴幼儿血管瘤组织中bFGF mRNA表达水平的研究
引用本文:林晓萍,刘维贤,高红,李吉,周永德. 婴幼儿血管瘤组织中bFGF mRNA表达水平的研究[J]. 中华小儿外科杂志, 2000, 21(5): 293-295
作者姓名:林晓萍  刘维贤  高红  李吉  周永德
作者单位:1. 110003,沈阳,中国医科大学第二临床学院口腔科
2. 中国医科大学第二临床学院儿外中心实验室
3. 中国医科大学基础医学院解剖教研室
摘    要:目的 探讨bFGF mRNA表达水平与婴幼儿血管瘤发生、发展的关系。方法 应用RT-PCR技术对34例婴幼儿血管瘤进行了bFGF mRNA表达的分析。结果 发现bFGF mRNA在所测组织中均有不同水平的表达升高。结论 提示bFGF mRNA与婴幼儿血管瘤的发生、发展有一定的关系。

关 键 词:聚合酶链反应 基因表达 血管瘤 婴幼儿
修稿时间:1999-07-12

Expression of bFGF and mRNA of hemangiomas in infants
LIN Xiaoping LIU Weixian,GAO Hong,et al. Expression of bFGF and mRNA of hemangiomas in infants[J]. Chinese Journal of Pediatric Surgery, 2000, 21(5): 293-295
Authors:LIN Xiaoping LIU Weixian  GAO Hong  et al
Affiliation:LIN Xiaoping LIU Weixian,GAO Hong,et al,Department of Stomatology,The 2nd Clinical College. China Medical University. Shenyang 110003,China
Abstract:Objective To investigate the relationship between the expression of bFGF and mRNA with the occurrence and progression of infantile hemangiomas. Methods The qualitative and quantitative study on bFGF and mRNA in 34 infants with hemangiomas was investigated by RT PCR technique, and normal parotid tissues around the hemangiomas ( n =5) served as controls. Results The expression of bFGF and mRNA was higher than those of the normal controls. Conclusion bFGF and mRNA might have important role in the occurrence and progression of hemangiomas.
Keywords:PCR  Gene expression  Hemangioma  Infants
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