| 无水酒精局部注射治疗复发性肝癌对癌细胞血行播散的影响 |
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| 引用本文： | 刘扬,宗明,张柏和,钱光相,杨甲梅,杨广顺,陈汉,吴孟超. 无水酒精局部注射治疗复发性肝癌对癌细胞血行播散的影响[J]. 中华普通外科杂志, 2002, 17(4): 207-208 |
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| 作者姓名： | 刘扬 宗明 张柏和 钱光相 杨甲梅 杨广顺 陈汉 吴孟超 |
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| 作者单位： | 200438,上海,第二军医大学东方肝胆外科医院 |
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| 摘 要： | 目的：探讨无水酒精局部注射（PEI）术治疗复发性肝癌对癌细胞血行播散的影响。方法：应用巢式RT－PCR检测复发性肝癌患者PEI术前后周围静脉血液中肝癌细胞的变化。结果：29例复发性肝癌患者PEI术前有14例（48％）周围血清中肝癌细胞阳性者；PEI治疗4次（1个疗程）后阳性者减至2例（7％）。结论：PEI治疗复发性肝癌可以有效地预防或阻止肝癌再复发及远处转移的发生。
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| 关 键 词： | 聚合酶链反应 局部注射 无水酒精 复发性肝癌 血行播散 |
| 修稿时间： | 2001-02-15 |
Peripheral blood determination of AFP mRNA in patients with recurrent hepatocellular carcinoma (HCC) undergoing percutaneous ethanol injection(PEI) |
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| LIU Yang,ZONG Ming,ZHANG Baihe,et al.. Peripheral blood determination of AFP mRNA in patients with recurrent hepatocellular carcinoma (HCC) undergoing percutaneous ethanol injection(PEI)[J]. Chinese Journal of General Surgery, 2002, 17(4): 207-208 |
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| Authors: | LIU Yang ZONG Ming ZHANG Baihe et al. |
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| Affiliation: | LIU Yang,ZONG Ming,ZHANG Baihe,et al. The Institute of East Hepatobiliary Surgery,Second Military Medical University,Shanghai 200433,China |
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| Abstract: | Objective To study the effect of PEI on disseminating HCC cells in the peripheral blood in patients with recurrent HCC. MethodsWe examined blood samples from 29 recurrent HCC patients by nested RT-PCR for the determination of AFP?mRNA before and 1, 2, 3 and 4 weeks after PEI.ResultsBefore PEI 14 (48%) patients out of the 29 cases with recurrent HCC were positive with AFP?mRNA. Four weeks after a course of PEI only 2 cases (7%) remained AFP?mRNA positive.ConclutionsPEI effectively eradicating disseminating HCC cells in the peripheral blood shows a favourable potential for the treatment of recurrent HCC. |
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| Keywords: | Carcinoma hepatocellular Polymerase chain reaction Neoplasm recurrence local |
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