垂体后叶素与酚妥拉明治疗大咯血疗效分析

目的：观察垂体后叶素，酚妥拉明两药单用和合用治疗大咯血的疗效。方法96例大咯血患者分3组：垂体后叶素组45例，采用注射垂体后叶素治疗；酚妥拉明组30例，注射酚妥拉明治疗；合用组21例：前二者同用，剂量稍减。比较3组患者治疗效果和不良反应情况。结果合用组总有效率为90.48%，高于垂体后叶素组和酚妥拉明组，与酚妥拉明组比较差异具有统计学意义（P＜0.05）；合用组不良反应率显著低于垂体后叶素组和酚妥拉明组（x2=4.7852、4.0728，P＜0.05）。结论大咯血患者治疗中，后叶素与酚妥拉明合用优于单独使用治疗效果，并且具有较少的副反应。

Clinical efficacy observation of vasopressin and phentolamine in treatment for massive hemoptysis

Objective To investigate clinical effect of vasopressin and phentolamine in treatment for massive hemoptysis. Methods 96 cases of hemoptysis patients were divided into three groups： 45 cases of posterior pituitary vasopressin group, treated with injection of vasopressin; 30 cases of phentolamine group, treated with injection of phentolamine; 21 cases combined group, treated with both dose diminished. The therapeutic effect and adverse reactions of three groups were analyzed. Results After treatment, the total effective rate of combined group was 90.48%, higher than the vasopressin group and the phentolamine group, compared to phentolamine group with a significant difference （P 〈 0.05）; The adverse reaction rate of combination group was significantly lower than that of the vasopressin group and phentolamine group （x2= 4.7852, 4.0728, P 〈 0.05）. Conclusion The vasopressin combined with phentolamine in treatment of patients with massive hemoptysis has superior therapeutic effects and has fewer side effects.