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| 脂肪细胞因子与非酒精性脂肪肝病 | |
| 引用本文： | 高娜,严谨,袁浩泳,欧阳冬生. 脂肪细胞因子与非酒精性脂肪肝病[J]. 中国临床药理学与治疗学, 2010, 15(4): 458-463 |
| 作者姓名： | 高娜 严谨 袁浩泳 欧阳冬生 |
| 作者单位： | 1. 中南大学临床药理研究所,长沙,410078,湖南 2. 中南大学湘雅三医院,长沙,410013,湖南 3. 中南大学基础医学院,长沙,410083,湖南 |
| 基金项目： | 湖南省科技计划资助项目，国家大学生创新性实验计划资助项目 |
| 摘 要： | 非酒精性脂肪肝病是发病率仅次于病毒性肝炎的常见肝病,是隐原性肝硬化的主要危险因素之一。多种脂肪细胞因子参与了脂肪肝的病理过程。本文就脂联素、瘦素、抵抗素、内脏脂肪素、Apelin、肠凝集素、网膜素等7种脂肪细胞因子与非酒精性脂肪肝的关系研究进展作一综述。 |
| 关 键 词： | 非酒精性脂肪肝 脂肪细胞因子 胰岛素抵抗 |
Adipocytokines and nonalcoholic fatty liver disease |
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| GAO Na,YAN Jin,YUAN Hao-yonga,OUYANG Dong-sheng. Adipocytokines and nonalcoholic fatty liver disease[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2010, 15(4): 458-463 | |
| Authors: | GAO Na YAN Jin YUAN Hao-yonga OUYANG Dong-sheng |
| Affiliation: | GAO Na,YAN Jin,YUAN Hao-yong,OUYANG Dong-sheng(1 Institute of Clinical Pharmacology,Central South University,Changsha 410078,Hunan,China; 2 The Third Xiangya Hospital of Central South University,Changsha 410013,Hunan,China; 3 School of Basic Medical Sciences,Central South University,Changsha 410083,Hunan,China ) |
| Abstract: | Nonalcoholic fatty liver disease （NAFLD）,one of the principal causes of cryptogenic cirrhosis,is the most common liver disease second to viral hepatitis.Adipocytokines contribute to fatty liver.We review the research progress of seven kinds of adipocytokines：adiponectin, lepin,resistin,visfatin,apelin,hep- cidin and omentin,which may be associated with the non-alcoholic fatty liver disease. |
| Keywords: | Nonalcoholic fatty liver disease Adipocytokine Insulin resistance |
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