| 73例香丹注射液不良反应文献分析 |
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| 引用本文： | 马春红.73例香丹注射液不良反应文献分析[J].中国中医药信息杂志,2014(6):33-34,37. |
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| 作者姓名： | 马春红 |
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| 作者单位： | 宜昌市第二人民医院药剂科,湖北宜昌443000 |
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| 摘 要： | 目的探讨香丹注射液药物不良反应(ADR)发生的特点及一般规律,为临床安全用药提供参考。方法检索2002-2012年国内医药期刊中香丹注射液致ADR的个案报告73例,对患者一般情况、药品用量及溶剂和ADR发生时间、临床表现及转归等有效信息进行统计分析。结果香丹注射液ADR临床表现主要是过敏性休克,发生率达46.58%(34/73);发生时间主要集中在用药后30 min内(46/73,63.01%)。结论合理使用中药注射剂的同时,应加强临床用药监测,尽量避免和减少香丹注射液ADR的发生。
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| 关 键 词： | 香丹注射液 药物不良反应 临床药学 |
Literature Analysis of 73 Cases of Adverse Reactions of Xiangdan Injection |
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| MA Chun-hong.Literature Analysis of 73 Cases of Adverse Reactions of Xiangdan Injection[J].Chinese Journal of Information on Traditional Chinese Medicine,2014(6):33-34,37. |
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| Authors: | MA Chun-hong |
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| Institution: | MA Chun-hong (Pharmacy Department, the Second Hospital of Yichang, Yichang 443000, China) |
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| Abstract: | Objective To discuss the features and general patterns of adverse drug reaction （ADR） of Xiangdan injection, and provide reference for clinical safe medication. Methods The author retrieved 73 cases about ADR of Xiangdan injection in domestic medicine journals from 2002 to 2012, collected and analyzed the information about patients’ general conditions, medicine dosage and solvent, ADR happening time, clinical manifestations, and prognosis. Results The main clinical manifestation of ADR was anaphylactic shock, with the incidence rate of 46.58%（34/73）, and the happening time was mainly within 30 minutes after the patients received Xiangdan injection （46/73, 63.01%）. Conclusion TCM injection should be used properly. At the same time, clinical medication monitoring should be strengthened, with a purpose to reduce and avoid ADR of Xiangdan injection. |
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| Keywords: | Xiangdan injection ADR clinical pharmacy |
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