锌剂联合去乳糖饮食佐治轮状病毒肠炎并发乳糖不耐受患儿疗效观察

目的探讨锌剂配合去乳糖饮食佐治轮状病毒肠炎并发乳糖不耐受患儿的效果。方法将100例轮状病毒肠炎并发继发性乳糖不耐受患儿分为观察组和对照组,每组50例,2组患儿均给予口服或静脉补液、复方胃蛋白酶散、蒙脱石散及酪酸梭菌二联活菌散等治疗。对照组患儿给予常规喂养,观察组患儿给予口服葡萄糖酸锌及无乳糖奶粉喂养。比较2组患儿的治疗效果、腹泻缓解时间及总病程。结果观察组和对照组患儿治疗总有效率分别为98.0%和86.0%,观察组患儿治疗总有效率显著高于对照组,差异有统计学意义(P<0.05)。观察组患儿腹泻缓解时间和总病程显著短于对照组,差异均有统计学意义(P<0.05)。结论口服锌剂联合去乳糖饮食佐治轮状病毒肠炎并发继发性乳糖不耐受能够缩短病程,减轻症状。

Effect of zinc and lactose-free diet in adjunctive treatment of infants with rotavirus enteritis and lactose intolerance

Objective To evaluate the effect of zinc and lactose-free diet in adjunctive treatment of infants with rotavirus enteritis and lactose intolerance. Methods One hundred infants with rotavirus enteritis and lactose intolerance were divided into observation group and control group,fifty cases in each group. The infants in the two groups were treated with fluid infusion（ by mouth or vein）,compound pepsin powder,montmorillonite powder,combined Clostridium butyricum and Bifidobacterium powders. The infants in control group were given routine feeding,but the infants in observation group were given zinc gluconate and lactose-free milk powder. The therapeutic efficacy,diarrhea remission time and total course of disease were compared between the two groups. Results The total effective rate in observation group and control group was 98. 0% and 86. 0%,respectively; the total effective rate in observation group was significantly higher than that in control group（ P 0. 05）. The diarrhea remission time and total course of disease in observation group were significantly shorter than those in control group（ P 0. 05）. Conclusion Zinc and lactose-free diet can significantly shorten the course of disease,lighten the symptom in treatment of infants with rotavirus enteritis and lactose intolerance.