Bifurcation stenting of unprotected common trunk: a case report and review of the literature]

Left main disease is the most severe form of atherosclerotic heart disease, with severe prognostic implications in the short-medium term. The traditional therapeutic approach has been surgical, with placement of bypass grafts both on the LAD and the circumflex artery. Published experience with the percutaneous approach to left main disease has been disappointing because of acute procedural problems and poor long-term outcome. On the other hand, a review of the literature shows a strong negative selection of patients offered PTCA of left main-stem lesions: most published series are composed of extremely high-risk patients, often in cardiogenic shock or with severe extracardiac multisystem disease, with a prohibitive surgical risk and an inherently poor acute and mid-term prognosis. We describe such a patient, a 77-year-old woman with end-stage renal disease on hemodialysis, who developed unstable angina due to distal critical left main disease, with involvement of the origin of both the LAD and the circumflex branch. Angina did not stabilize with medical therapy; the patient was denied surgery because of a prohibitively high surgical risk. A bifurcation stenting procedure was performed with no acute complications, a satisfactory one-month angiographic follow-up and no recurrence of angina until the death of the patient 4 months after the procedure for extracardiac reasons. As indicated by a recent paper by M. Leon, we likewise suggest that left main disease (especially in its simpler proximal variants) may actually be a good target for state-of-the-art transcatheter interventions, including primary stenting, under close angiographic follow-up and careful positive (instead of negative) selection of patients.