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Nicorandil-induced severe oral ulcerationA newly recognized drug reaction
Authors:R.H. Shotts MB BS   FDSRCS a   C. Scully MD   PhD   MDS   FDSRCPS   FDSRCS   FFDRCSI   FDSRCSE   FRCPath   FMedSci  a   C.M. Avery FDSRCS   FRCS b  S.R. Porter MD   PhD   FDSRCS   FDSRCSEa  
Affiliation:Department of Oral Medicine, Eastman Dental Institute of Oral Health Care Sciences, University of London, United Kingdom.
Abstract:Nicorandil, a potassium-channel activator used for the long-term treatment of ischemic heart disease, has been recently implicated as having a drug side effect of recurrent aphthous stomatitis. Three patients are reported with drug-induced aphthouslike ulceration secondary to nicorandil.
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