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Sirolimus for the treatment of multi-resistant pure red cell aplasia
Authors:Huijuan Jiang  Huiqin Zhang  Yihao Wang  Weiwei Qi  Qiuying Cao  Limin Xing  Rong Fu  Zonghong Shao  Huaquan Wang
Affiliation:Department of Haematology, General Hospital, Tianjin Medical University, Tianjin, China
Abstract:Patients with relapsed, refractory or advanced stage B non-Hodgkin lymphoma (NHL) continue to have a dismal prognosis. This review summarises current and novel cellular and immunotherapy for these high-risk populations, including haematopoietic stem cell transplant, bispecific antibodies, viral-derived cytotoxic T cells, chimeric antigen receptor (CAR) T cells, and natural killer (NK) cell therapy, as discussed at the 6th International Symposium on Childhood, Adolescent and Young Adult Non-Hodgkin Lymphoma on September 26th–29th 2018 in Rotterdam, the Netherlands, and explores the future of NK/CAR NK therapies.
Keywords:sirolimus  pure red cell aplasia  therapy
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