| 高尿酸血症并腹型肥胖动物模型研究进展 |
| |
| 引用本文： | 林志健,张冰,黄胜男,李丽玉.高尿酸血症并腹型肥胖动物模型研究进展[J].实验动物与比较医学,2014,22(4):81-85. |
| |
| 作者姓名： | 林志健 张冰 黄胜男 李丽玉 |
| |
| 作者单位： | 北京中医药大学, 北京 100029;北京中医药大学, 北京 100029;北京中医药大学, 北京 100029;北京中医药大学, 北京 100029 |
| |
| 基金项目： | 教育部高等学校博士学科点专项科研基金（NO. 20130013120001，20120013130002）；北京中医药大学科研创新团队（2011-CXTD-014）；北京中医药大学自主课题（2013-QNJSZX008）。 |
| |
| 摘 要： | 随着人类生活方式和饮食结构的改变，高尿酸血症和腹型肥胖的发病率逐年升高，且临床研究发现高尿酸血症与腹型肥胖经常在同一个体上出现，两者密切相关。研究发现高尿酸血症并腹型肥胖已成为常见的代谢性疾病，是心脑血管疾病的危险因子。高尿酸血症并腹型肥胖模型的研究，对于阐释高尿酸血症并腹型肥胖的病理及药理机制十分重要。本文就高尿酸血症并腹型肥胖动物模型研究进展进行综述。
|
| 关 键 词： | 高尿酸血症 腹型肥胖 动物模型 |
| 收稿时间： | 2014/4/6 0:00:00 |
Advances in research of animal models of hyperuricemia combined with abdominal obesity |
| |
| LIN Zhi-jian,ZHANG Bing,HUANG Sheng-nan and LI Li-yu.Advances in research of animal models of hyperuricemia combined with abdominal obesity[J].Laboratory Animal and Comparative Medicine,2014,22(4):81-85. |
| |
| Authors: | LIN Zhi-jian ZHANG Bing HUANG Sheng-nan and LI Li-yu |
| |
| Institution: | Beijing University of Chinese Medicine, Beijing 100029, China;Beijing University of Chinese Medicine, Beijing 100029, China;Beijing University of Chinese Medicine, Beijing 100029, China;Beijing University of Chinese Medicine, Beijing 100029, China |
| |
| Abstract: | Hyperuricemia is closely associated with abdominal obesity. The prevalence of hyperuricemia combined with abdominal obesity has been increased significantly in recent years, along with the improvement of daily life and the changes in dietary structure. The state of hyperuricemia combined with abdominal obesity is most harmful, and becomes a common and high risk metabolic disease. Animal model with hyperuricemia combined with abdominal obesity is very important for the research of pathomechanism and treatment of this disease. |
| |
| Keywords: | Hyperuricemia Abdominal obesity Animal models |
|
| 点击此处可从《实验动物与比较医学》浏览原始摘要信息 |
| 点击此处可从《实验动物与比较医学》下载免费的PDF全文 |
