| 兔食管静脉曲张模型的建立 |
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| 引用本文： | 刘翔宇,孙自勤,刘传照,魏志,杨鹏,李义,孙艾茜.兔食管静脉曲张模型的建立[J].实验动物与比较医学,2013,21(3). |
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| 作者姓名： | 刘翔宇 孙自勤 刘传照 魏志 杨鹏 李义 孙艾茜 |
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| 作者单位： | 济南军区总医院,济南军区总医院,济宁市第一人民医院,济南军区总医院,济南军区总医院,济南军区总医院,济南军区总医院 |
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| 摘 要： | 目的 建立新西兰大白兔的食管静脉曲张模型，为下一步的临床研究提供可靠的小动物型模型。方法 采用门静脉左支完全夹闭法造模，并通过外观、超声、胃镜等检查检验手段对造模结果加以评估。结果 术后8周100%存活动物可见食管静脉曲张。结论 通过门静脉左支夹闭法，基本可以建立兔食管静脉曲张模型。
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| 关 键 词： | 兔 动物模型 食管静脉曲张 |
| 收稿时间： | 2012/12/25 0:00:00 |
| 修稿时间： | 2013/1/17 0:00:00 |
Establishment of Esophageal Varices in Rabbits |
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| liyi and Sun Aixi.Establishment of Esophageal Varices in Rabbits[J].Laboratory Animal and Comparative Medicine,2013,21(3). |
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| Authors: | liyi and Sun Aixi |
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| Institution: | Jinan Military General Hosptial,Jinan Military General Hosptial |
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| Abstract: | AIM: To establish a the esophageal varices model of New Zealand white rabbits, reliable small animal model for further clinical studies.
METHODS: Twenty rabbits were used in the study. Esophageal varices were estalished by complete ligation of the left portal vein.
RESULTS: All the rabbits who survived had developed esophageal varices that were demonstrated by endoscopy.
CONCLUSION: A rabbit model of Esophageal Varices be established sueeessfully with this method. |
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| Keywords: | rabbit animal model Esophageal Varices |
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