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原位活体部分肝移植五例报告
引用本文:王学浩,张峰,李相成,钱建民,孔连宝,黄祖瑚,徐鑫荣,傅诚章,刘存明,陈吉庆,何祚光,陆化,胡淑芳,林红军,李军,张浩,孙倍成.原位活体部分肝移植五例报告[J].中华器官移植杂志,2001,22(5):285-287.
作者姓名:王学浩  张峰  李相成  钱建民  孔连宝  黄祖瑚  徐鑫荣  傅诚章  刘存明  陈吉庆  何祚光  陆化  胡淑芳  林红军  李军  张浩  孙倍成
作者单位:1. 南京医科大学第一附属医院肝脏移植中心
2. 南京医科大学第一附属医院传染科
3. 南京医科大学第一附属医院ICU
4. 南京医科大学第一附属医院麻醉科
5. 南京医科大学第一附属医院儿科
6. 南京医科大学第一附属医院血液科
7. 南京医科大学第一附属医院B超室
基金项目:江苏省政府重点课题资助项目(BJ98025);江苏省青年基金项目(BQ9802);江苏省卫生厅重点项目(H9517)
摘    要:目的:总结活体肝移植的临床经验与教训。方法:对5例原位活体部分肝移植的临床资料进行回顾性分析。结果:5名供者术后均顺利康复;5例患者手术顺利,4例原发病为肝豆状核变性者术后健康存活,现已分别存活21周,15周,12周及2周;1例肝癌患者移植术后12d死于心律紊乱,心跳骤停;术后并发症以血管并发症,胆道并发症,细菌及病毒感染和肺部并发症为主。结论:原位活体部分肝移植手术过程复杂,技术要求高,难度大;具有其它类型肝移植无法比似的优越性。

关 键 词:肝移植  活体供者  临床研究  病例报告

Report of 5 cases of living related liver transplantation
Abstract:Objective To evaluate the clinical application of living related liver transplantation. Methods A retrospective analysis was made in 5 cases (1 case of hepatocellular carcinoma and 4 of Wilson's disease) undergoing living related liver transplantation from 1995 to now. The experience of surgical techenique, the perioperative treatments, the diagnosis and treatment of complications in these 5 cases were summarized. Results All the operations of 5 cases were successful. The 5 donors recovered uneventfully. Four recipients with Wilson's disease have been surviving 21 weeks,15 weeks,12 weeks and 2 weeks respectively. The process of operation was complicated, and the surgical technique was difficult. The complications of vlood vessel, biliary tract and lung and the infection of bactera and viruses after operation were dominant. The allograft rejection was infrequent. Conclusions Living related liver transplantation has many unsurpassed advantages. It is suitable for the situation of China and can be used extensively in clinical liver transplantation.
Keywords:Liver transplantation  Living donors  Clinical studies
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