| 多发性骨髓瘤的个体型阳性细胞检查及意义 |
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| 引用本文： | 米丰年,菅井进,绀田进. 多发性骨髓瘤的个体型阳性细胞检查及意义[J]. 中国免疫学杂志, 1987, 0(3) |
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| 作者姓名： | 米丰年 菅井进 绀田进 |
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| 作者单位： | 牡丹江医学院血液病研究室，日本金沢医科大学，日本金沢医科大学 牡丹江 |
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| 摘 要： | 近年来抗个体型抗体(antiidiotypeantibodies,抗Id抗体)的理论研究及应用有了迅速地发展,已成为免疫学研究中活跃领域之一。个体型是指在同一个体内,不同的抗体形成细胞所产生的免疫球蛋白(Ig)有各自不同的抗原特异性。决定个体型抗原特异性的部位在抗体可变区的超可变区,是针对超可变区某些抗原决定簇的抗体。在
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Clinical significance the positive idiotype in patients with multiple myeloma |
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| Mi Fen-nian,et al. Clinical significance the positive idiotype in patients with multiple myeloma[J]. Chinese Journal of Immunology, 1987, 0(3) |
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| Authors: | Mi Fen-nian et al |
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| Affiliation: | Hematology Department of Mudanjiang Medical College |
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| Abstract: | This article reported a method of anti idiotype antibodies to idiotype in patientswith multiple myeloma.SmIg and CIg of peripheral blood lymphocytes of patientswith multiple myeloma were examined by using anti idiotype antibodies. The result revealed that(1)the anti idiotype antibody only reacted to M pro-tein and serum of the patient,but not to M proteinemia and normal Ig.(2)SmIg andCIg of some B cell reacted to the antiidiotype antibodies,it has been suggestedthatthe abnormal colon of multiple myeloma formed in B cell |
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| Keywords: | Anti idiotype antibody Surface membrane Immunoglobulin Intracytoplasmic immunoglobulin |
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