3820例呼吸道感染患儿病原体的检测结果及流行病学特点分析

目的:了解垫江地区儿童呼吸道病原体流行情况,为疾病的预防和诊治提供实验室依据.方法:回顾性分析2018年1月至2020年10月本院收治的3820例呼吸道感染患儿入院时检测的血常规、血清淀粉样蛋白A(Serum amyloid A,SAA)、C反应蛋白(C-reactive protein,CRP)结果及采用间接免疫荧光...

Analysis of respiratory pathogens and epidemiological characteristics of 3820 children with respiratory tract infection

Objective:To understand the prevalence of respiratory pathogens in children in Dianjiang area,in order to provide laboratory basis for disease prevention and diagnosis.Methods:The results of serum amyloid A(SAA),Creactive protein(CRP)and eleven IgM antibodies of respiratory pathogens detected by indirect immunofluorescence assay in 3820 children with respiratory tract infection admitted to our hospital from January 2018 to October 2020 were retrospectively analyzed.Results:The total detection rate of virus IgM antibody was 51.65%(1973/3820),and INFB,INFA and MP were the main infections;Among the 1,973 patients who tested positive for respiratory pathogens,321 patients had mixed infection,and the mixed infection rate was 16.27%.The positive rate of female children was higher than that of male children(P=0.002).The positive rate of respiratory pathogens was higher in preschool group and school-age group,and lowest in infant group,and the difference was statistically significant(P<0.05).The positive pathogen detection rate in summer was significantly lower than that in other three seasons(P=0.00);CP group had the highest SAA level,which was significantly higher than PIV group(P<0.05),WBC of INFA group and RSV group were significantly higher than those of the other 4 groups.In INFA group,mononuclear cell proliferation was dominant,while lymphocyte proliferation was dominant in RSV group.Conclusion:INFB,INFA and MP are the main respiratory infection pathogens in children in Dianjiang area.There were significant differences in pathogen infection rates among different genders,ages and seasons.In addition,the results of laboratory tests after infection with different types of pathogens are also different,so effective measures should be taken to prevent infection and make reasonable diagnosis and treatment.