| 白细胞介素2和黄芪多糖对小鼠NK细胞作用的细胞化学和超微结构观察 |
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| 引用本文： | 张晓明,杨景山.白细胞介素2和黄芪多糖对小鼠NK细胞作用的细胞化学和超微结构观察[J].解剖学报,1991(1). |
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| 作者姓名： | 张晓明 杨景山 |
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| 作者单位： | 北京医科大学组织学胚胎学教研室，北京医科大学组织学胚胎学教研室 北京 100083，北京 100083 |
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| 摘 要： | 本文报道在白细胞介素2(IL-2)及黄芪多糖(PA)作用下,小鼠NK细胞的细胞化学和超微结构变化。实验表明,NK细胞酸性磷酸酶、酸性醋酸酯酶及氯醋酸AS-D酯酶均为阳性。经IL-2和PA的处理,前两种酶的活性增加,阳性细胞百分率增高,并与NK活性相关。IL-2培养后的NK细胞超微结构表现为胞体变大,表面不规则,胞质丰富,细胞器增多等特点。
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| 关 键 词： | 白细胞介素2 黄芪多糖 酸性磷酸酶 酸性醋酸酯酶 氯醋酸AS-D酯酶 细胞化学 超微结构 |
EFFECTS OF INTERLEUKIN-2 AND POLYSACCHARIDE OF ASTRAGALUS ON MURINE NK CELL: CYTOCHEMISTRY AND ULTRASTRUCTURE |
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| Zhang Xiaoming,Yang Jingshan.EFFECTS OF INTERLEUKIN-2 AND POLYSACCHARIDE OF ASTRAGALUS ON MURINE NK CELL: CYTOCHEMISTRY AND ULTRASTRUCTURE[J].Acta Anatomica Sinica,1991(1). |
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| Authors: | Zhang Xiaoming Yang Jingshan |
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| Abstract: | In this paper, murine natural killer (NK) cells were studied with cytochemistry and electron-microscopy after treated with interleukin-2 (IL-2) and polysaccharide of astragalus (PA). The results showed that acid phosphatase (AcP), acid naphthylacetate esterase (ANAE) and naphthol-AS-D chloroacetate esterase (NCAE) were positive in NK cells, and the activity of AcP and ANAE was enhanced by IL-2 and PA. Significant changes of NK cells in ultrastructure took place after preculturing with IL-2. |
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| Keywords: | Interleukin-2 (IL-2) Polysaccharide of astragalus (PA) Acid phosphatase (AcP) Acid naphthyl acetate esterase (ANAE) Cytochemistry Ultrastructure |
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