The effect of scopolamine on fetal heart rate baseline variability

The effect on FHR baseline variability of intravenous scopolamine (0.43 mg.) administered alone and in combination with Demerol (50 mg.) and Largon (20 mg.) was evaluated. A decrease in baseline variability was found in nine of 19 patients given scopolamine (0.43 mg.). When scopolamine, Demerol, and Largon were infused simultaneously, a change in baseline variability was observed in nine of 12 patients. No change in variable or early deceleration FHR patterns was observed.