| Innovar预防气管插管反应的实验 |
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| 引用本文： | 曾祥龙 朱妙章. Innovar预防气管插管反应的实验[J]. 医学争鸣, 1992, 13(4): 307-310 |
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| 作者姓名： | 曾祥龙 朱妙章 |
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| 作者单位： | 西京医院麻醉科(曾祥龙，陈绍洋，熊利泽，李桂科)，第四军医大学生理学教研室(朱妙章，臧益民)，第四军医大学生理学教研室(王跃民) |
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| 摘 要： |
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| 关 键 词： | 插管法 血液动力学 芬太尼 氟哌啶 |
Prevention of cardiovascular response to endotracheal intubation with innovar in rabbit |
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| ZENG Xiang-Long CHEN Shao Yang,ZHU Miao-Zhang,XIONG Li-Ze LI Gui-KeZANG Yi-Min and WANG Yue-Min. Prevention of cardiovascular response to endotracheal intubation with innovar in rabbit[J]. Negative, 1992, 13(4): 307-310 |
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| Authors: | ZENG Xiang-Long CHEN Shao Yang ZHU Miao-Zhang XIONG Li-Ze LI Gui-KeZANG Yi-Min WANG Yue-Min |
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| Affiliation: | ZENG Xiang-Long CHEN Shao Yang,ZHU Miao-Zhang,XIONG Li-Ze LI Gui-KeZANG Yi-Min and WANG Yue-MinDepartment of Anaesthesia,Xijing Hospital Department of Physiology |
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| Abstract: | Changes of ABP, LVP, dp/dt and CO in 12 rabbits were observed respectively at 0, 1, 3, 5 and 10 min after placing laryngoscope and endotracheal intubation (E1). E1 was done 5 min after intravenous administration of innovar (0.1 ml/kg) in experimental group. Results showed that in control group, MAP increased significantly (P<0.05) at 1 and 3 min after E1, RPP increased significantly at 0 (P<0.05) and 1 min (P<0.01) after EI. LVSP increased at the time of placing laryngoscope and at 0, 1 min after EI (P<0.05). There were no obvious changes in HR, CO, dp/dtmax and t-dp/dtmax. In experimental group, there were no significant changes in RPP, HR, MAP, CO and t-dp>/dtmax. LVSP and dp/dtmax decreased significantly (P<0.05) at 1, 3 and 5 min after EI. It was con-cluded that 5 min after intravenous administration of innovar was the best point for EI, in which increase of RPP and stress stimulated by EI were prevented without changes of MAP and CO. |
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| Keywords: | intubation intratracheal hemodynarnics ientanyl droperidol rabbits |
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