集中空调冷却塔军团菌污染对宾馆从业人员血清军团菌抗体的影响

目的尽管很多公共场所的冷却塔的进行定期消毒,但是我们江苏常州市进行的调查依然在89.6%冷却塔水样品中检出了的军团菌。本研究的目的是探索这些军团菌污染的冷却塔对从业人员健康的影响。方法从公共场所从业人员中随机选取364名对象进行血清抗体测试和问卷调查。暴露组来自1型嗜肺军团菌污染的冷却塔所在场所的从业人员,对照组对象来自没有使用的集中空调的场所。血清军团菌抗体的检测采用间接免疫荧光(IFA)的方法。结果暴露组对象的1型嗜肺军团菌抗体的阳性率显著性高于对照组(OR=2.845,P=0.019)。自来水和淋浴水中的军团菌污染可能是混杂因素。其中暴露组人群感冒症状的的发生频率显著性高于对照组,室内空气质量的满意度也与1型嗜肺军团菌抗体的阳性率相关。结论嗜肺军团菌污染的冷却塔与场所从业人员血清军团菌抗体的阳性率相关,自来水和淋浴水中的军团菌也是可能的污染源。

The effects of Cooling Towers on the high Seroprevalence of Legionella pneumophila antibody among hotel workers

Objective Regular disinfection work of the cooling towers （CTs） were carried out according to schedule, nevertheless 89.6% of the CTs were still found to be colonized by L.pneumophila in our survey in Changzhou city, China. The aim of the study was to observe the effect of Legionella pneumophila （L. pneumophila） on Workers exposed to contaminated CTs. Methods A total of 364 subjects were randomly selected for the serum testing and the questionnaire survey, from the hotel with contaminated CTs or without CTs （used as control）. Their serum anti-L, pneumophila antibodies were tested using commercial IFA kits. Results The results showed that the prevalence of anti-L, pneumophila serogroup 1 antibodies in the exposed population was significantly higher than control subjects （OR=2.845, P=0.019）. The possible confounding factors were analyzed. Questionnaires results analysis found the frequency of flu-like symptoms in exposed group was also significantly higher; and the indoor air quality was related to the serum anti-L.pneumophila serogroup 1. Conclusion The L.pneumophila contaminated CTs contribute to the high seroprevalence of anti-L.pneumophila antibodies; tap water and shower water are also possible contamination resources.