急性重症高原病患者脑功能损伤与多器官功能障碍

目的 探讨急性重症高原病患者脑损伤与多脏器功能障碍的关系。方法 回顾性调查了50年间住院治疗的3184例急性重症高原病患者，对其脑损伤与多脏器功能障碍之间的关系进行了统计分析。结果 急性高原病患者中5．4％有不同程度昏迷，5％有精神异常，4％有嗜睡，1％有感觉异常，1.48％有眼底出血或水肿，1％有颅内CT异常；在这部分病人中高原脑水肿占总病例数的10％，在高原脑水肿病例中脑功能障碍比例明显增高，其中精神行为异常者占51％．有不同程度昏迷者占51．5％。脑功能障碍者中有15％伴其它脏器功能损伤，明显高于其它脏器损伤所伴有的并发症。结论 高原病患者脑损伤更易并发其它多脏器功能障碍，是引起高原多脏器功能障碍综合征的一个重要原因。

Relationship between severe cerebral injury and multiple organ dysfunction syndrome in acute serious mountain sickness

Objective To confer the relationship between cerebral dysfunction and multiple organ dysfunction syndrome (MODS) in acute serious mountain sickness. Methods Retrospectively surveyed 3 184 patients who were suffered by acute serious mountain sickness in the past 50 years, did statistical analysis of the relationship between cerebral dysfunction and MODS about these patients. Results In these patients who suffered acute mountain sickness, 5.4%had coma in different grades, 5% had abalienation, 4% had lethargy, 1% had paresthesia cacesthesia, 1.48% had eyeground haemorrhage or eyeguound edema, 1% had aberrated in intracranial CT. And in these patients, high altitude cerebral edema took one tenth in total. In high altitude cerebral edema patients, the inverse proportion of cerebral dysfunction had obvious increase, among them 51% had psychosis and dystrophy, 51.5% had coma in different grades. In these patients who had cerebral dysfunction, 15% accompanied by other visceral organs injury complication. Conclusion It's more easy had MODS in cerebral injury of acute mountain sickness patients, and cerebral injury also was a very important reason in high altitude MODS.